24-hour Movement Behaviors Among Type 2 Diabetes Mellitus Patients

NCT ID: NCT04993482

Last Updated: 2023-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

248 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-29

Study Completion Date

2026-12-01

Brief Summary

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A healthy lifestyle has proved beneficial health effects in managing type 2 diabetes mellitus (T2DM). Important lifestyle behaviors, i.e. sleep, sedentary time (SB), and physical activity (PA) subdivided into light physical activity (LPA) and moderate to vigorous physical activity (MVPA), have shown an impact on T2DM disease-specific characteristics (e.g. glycemic control). However, these behaviors have often been investigated separately. Therefore, a recent shift in research emphasizes the importance of considering these behaviors as part of a 24-hour day.

Since T2DM patients can benefit from an optimal 24-hour composition as part of a healthy lifestyle, it may be interesting to investigate the 24-hour movement composition among these T2DM patients over time. Moreover, exploring associations with different personal determinants, environmental determinants, and cardiometabolic markers will provide meaningful insights in developing recommendations and creating an intervention.

Detailed Description

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The present study aims (1) to conduct a longitudinal observational study over two years to explore 24-hour movement behavior composition patterns among T2DM patients in comparison with a healthy control group and (2) to examine associations between these movement behaviors and personal and environmental determinants, and cardiometabolic markers. This study's primary endpoint is to develop insights into the 24-hour movement composition combined with T2DM patients' characteristics, determinants, and health profile to set the groundwork with the aim to develop, implement and evaluate an intervention in a future randomized controlled trial

Conditions

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Diabetes Mellitus, Type 2

Keywords

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physical activity sedentary behavior sleep

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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type 2 diabetes mellitus group

124 adults with type 2 diabetes mellitus will be included

No intervention

Intervention Type OTHER

This project contains a longitudinal observational study design. The investigator will collect data out of a group with type 2 diabetes mellitus patients and out of group with control adults on three time points (baseline, follow-up after one year, and follow-up after two years). Therefore, the investigator will only collect observational data and the participants will not be exposed to a certain intervention.

control group

124 control adults will be included

No intervention

Intervention Type OTHER

This project contains a longitudinal observational study design. The investigator will collect data out of a group with type 2 diabetes mellitus patients and out of group with control adults on three time points (baseline, follow-up after one year, and follow-up after two years). Therefore, the investigator will only collect observational data and the participants will not be exposed to a certain intervention.

Interventions

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No intervention

This project contains a longitudinal observational study design. The investigator will collect data out of a group with type 2 diabetes mellitus patients and out of group with control adults on three time points (baseline, follow-up after one year, and follow-up after two years). Therefore, the investigator will only collect observational data and the participants will not be exposed to a certain intervention.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adults aged \>18 years old
* Diagnosed with T2DM by a physician or an HbA1C above 6.5%


\- Adults aged \> 18 years old

Exclusion Criteria

* Diagnosed with type 1 diabetes mellitus (T1DM)
* Diagnosed with pregnancy diabetes
* Diagnosed with latent autoimmune diabetes in adults (LADA)
* Physical disabilities that obstruct the normal PA pattern (e.g. amputations, paralysis)
* Cognitive disabilities that obstruct daily functioning (e.g. dementia, psychological disorders)
* Other conditions affecting the normal PA pattern (e.g. heart failure NYHA class 3 and 4, chronic respiratory diseases (COPD stage 4), end stage nonalcoholic fatty liver disease, end stage renal failure, cancer, hospitalized)
* Pregnancy or pregnancy \<1 year ago
* Participating in a physical activity intervention


* Diagnosed with T2DM
* Diagnosed with T1DM
* Diagnosed with pregnancy diabetes
* Diagnosed with LADA
* Physical disabilities that obstruct the normal PA pattern (e.g. amputations, paralysis)
* Cognitive disabilities that obstruct daily functioning (e.g. dementia, psychological disorders)
* Other conditions affecting the normal PA pattern (e.g. heart failure NYHA class 3 and 4, chronic respiratory diseases (COPD stage 4), end stage nonalcoholic fatty liver disease, end stage renal failure, cancer, hospitalized)
* Pregnancy or pregnancy \<1 year ago
* Participating in a physical activity intervention
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Ghent

OTHER

Sponsor Role collaborator

University Hospital, Ghent

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bruno Lapauw, Professor

Role: PRINCIPAL_INVESTIGATOR

Ghent University Hospital - endocrinologist

Marieke De Craemer, Professor

Role: PRINCIPAL_INVESTIGATOR

University Ghent

Locations

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Ghent University Hospital, Dept. of Endocrinology

Ghent, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Iris Willems, PhD student

Role: CONTACT

Phone: 093323638

Email: [email protected]

Marieke De Craemer, Professor

Role: CONTACT

Phone: 09 332 52 08

Email: [email protected]

Facility Contacts

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Bruno Lapauw, MD, PhD

Role: primary

Other Identifiers

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BC-10189

Identifier Type: -

Identifier Source: org_study_id