The Use of AR / VR in Patients Presenting to the ED With Renal Colic

NCT ID: NCT07070401

Last Updated: 2025-07-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

92 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-01

Study Completion Date

2026-03-31

Brief Summary

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Utilization of VR / AR Calming as an adjunct to pharmacologic pain management for Renal Colic in Emergency Department Patients

Detailed Description

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This study will randomize ED patients presenting for presumed renal colic to either standard pharmacologic pain management alone, or pharmacologic management plus use of an adjunct Virtual / Augmented reality calming application using an off-the-shelf VR/AR Headset.

Conditions

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Renal Colic Kidney Stones, Urolithiasis, Hypocitraturia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Trial between Standard of Care vs Standard of Care + Adjunct AR Calming
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard of Care Pharmacologic Management

Patients receive standard of care pharmacologic management at the discretion of the treating provider

Group Type ACTIVE_COMPARATOR

Pharmacologic Standard of Care Alone

Intervention Type OTHER

Pharmacologic Standard of Care Alone

AR Adjunct Plus Standard of Care Pharmacologic Management

Patients receive adjunct AR Calming App via commercial AR/VR headset in addition to standard of care pharmacologic management at the discretion of the treating provider

Group Type EXPERIMENTAL

Commercial AR/VR Headset with Calming App

Intervention Type DEVICE

Commercial AR/VR Headset with Calming App in addition to Pharmacologic Standard of Care

Interventions

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Commercial AR/VR Headset with Calming App

Commercial AR/VR Headset with Calming App in addition to Pharmacologic Standard of Care

Intervention Type DEVICE

Pharmacologic Standard of Care Alone

Pharmacologic Standard of Care Alone

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient self-reported history of nephrolithiasis
* Subjective history suggesting that current presentation is similar to past presentations of nephrolithiasis (character, quality, location, intensity of pain; previous surgical intervention or lithotripsy)
* Patients with self-reported moderate to severe pain on the visual pain scale determined as greater than 5/10
* Normal vital signs (afebrile)
* Agreeable to informed consent as dictated by IRB and local practice
* No contraindications to standard therapy (ie fluids, NSAIDs, opioids, etc.)
* Compliance with the virtual reality treatment
* Keeps the headset on for the duration of the experience
* Understands the instructions

Exclusion Criteria

* Age \< 18 years
* Pregnant
* Individuals with chronic pain conditions such as fibromyalgia (chronic pain may confound results, as patients may have higher than baseline pain levels affecting their response to medications)
* Individuals with severe anxiety or claustrophobia
* Individuals with severe motion sickness or previous episodes of motion sickness due to VR (those who may not react well to the VR experience)
* Individuals with GFR\<60 or previous documented diagnosis of CKD as they may not be suitable candidate for traditional analgesia
* Individuals with previous opioid dependence
* Requirement of immediate surgery (obstructing calculi with concomitant urinary tract infection)
* Patients with diagnoses meeting admission criteria (sepsis, MI)
* Audio/visual impairment (unable to appreciate stimuli provided by the headset)
* Patients administered opiates as the first line pain control medication will not be included in final data collection, as opioid administration may result in difficulty consenting and understanding the study protocol / design
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Community Medical Center, Toms River, NJ

OTHER

Sponsor Role lead

Responsible Party

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Greg Neyman

Research Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Chris Delmaestro, DO

Role: PRINCIPAL_INVESTIGATOR

Rutgers RWJBH Community Medical Center

Locations

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Rutgers Robert Wood Johnson Barnabas Health Community Medical Center

Toms River, New Jersey, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Greg Neyman, MD

Role: CONTACT

732.557.3242

Facility Contacts

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Greg Neyman, MD

Role: primary

732.557.3242

References

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Weynants L, Chys B, D'hulst P, Merckx L, Van Besien J, Tailly T. Virtual reality for pain control during shock wave lithotripsy: a randomized controlled study. World J Urol. 2023 Feb;41(2):589-594. doi: 10.1007/s00345-023-04280-8. Epub 2023 Jan 21.

Reference Type BACKGROUND
PMID: 36680576 (View on PubMed)

Pourmand A, Davis S, Marchak A, Whiteside T, Sikka N. Virtual Reality as a Clinical Tool for Pain Management. Curr Pain Headache Rep. 2018 Jun 15;22(8):53. doi: 10.1007/s11916-018-0708-2.

Reference Type BACKGROUND
PMID: 29904806 (View on PubMed)

Mallari B, Spaeth EK, Goh H, Boyd BS. Virtual reality as an analgesic for acute and chronic pain in adults: a systematic review and meta-analysis. J Pain Res. 2019 Jul 3;12:2053-2085. doi: 10.2147/JPR.S200498. eCollection 2019.

Reference Type BACKGROUND
PMID: 31308733 (View on PubMed)

Gottlieb M, Long B, Koyfman A. The evaluation and management of urolithiasis in the ED: A review of the literature. Am J Emerg Med. 2018 Apr;36(4):699-706. doi: 10.1016/j.ajem.2018.01.003. Epub 2018 Jan 5.

Reference Type BACKGROUND
PMID: 29321112 (View on PubMed)

Holdgate A, Pollock T. Systematic review of the relative efficacy of non-steroidal anti-inflammatory drugs and opioids in the treatment of acute renal colic. BMJ. 2004 Jun 12;328(7453):1401. doi: 10.1136/bmj.38119.581991.55. Epub 2004 Jun 3.

Reference Type BACKGROUND
PMID: 15178585 (View on PubMed)

Epidemiology of Nephrolithiasis. Course on Advances in Nephrology and Dialysis

Reference Type BACKGROUND

Worcester EM, Coe FL. Nephrolithiasis. Prim Care. 2008 Jun;35(2):369-91, vii. doi: 10.1016/j.pop.2008.01.005.

Reference Type BACKGROUND
PMID: 18486720 (View on PubMed)

Related Links

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https://cdphe.colorado.gov/sites/cdphe/files/OEPR5_CI_PainScales.pdf

Colorado Department of Public Health and Environment. Pain Scales. Colorado Department of Public Health and Environment, 2024

Other Identifiers

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25-001

Identifier Type: -

Identifier Source: org_study_id

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