Lithotripsy and Analgesia With 3D Hypnosis Mask

NCT ID: NCT04869293

Last Updated: 2023-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

106 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-15

Study Completion Date

2024-02-29

Brief Summary

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The study is a randomised trial of hypnosis with 3D virtual reality headset (intervention group) versus control group with no hypnosis and no virtual reality headset to compare remifentanil consumption during shock wave lithotripsy.

Detailed Description

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The study is for patients undergoing shock wave lithotripsy in outpatient surgery unit.

It is proposed that using hypnosis with 3D virtual reality headset will reduce the requirements for intravenous remifentanil in a randomised controlled trial of one hundred and six patients.

Remifentanil is an opioid commonly used for lithotripsy. Shock wave lithotripsy is a commonly performed procedure associated with moderate pain and anxiety, in outpatient surgery unit. Opioids can cause unfavourable side-effects, most notably respiratory depression, sedation, nausea and vomiting

It is expected that by using 3D virtual reality to reduce pain and anxiety, there will be a reduced requirement for intravenous remifentanil.

The study will measure the dose of remifentanil required by patients randomised to receive either hypnosis with 3D virtual reality headset (intervention) or no hypnosis and no 3D virtual reality headset (control group).

Patients will be followed up prior to hospital discharge to assess their remifentanil use and pain, anxiety, comfort and their satisfaction with 3D virtual reality headset.

This new device is a non-pharmacological adjunct and can reduce pain intensity during procedure, reduce opioid use and length of stay in hospital and improve the patient experience whilst potentially reducing complications of intravenous opioid.

This study findings will be of interest for patients involved in surgery or investigative procedures normally carried out with intravenous opioids or sedation.

Conditions

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Renal Calculi Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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3D virtual reality

Use of Hypnosis 3D virtual reality headset

Group Type EXPERIMENTAL

Hypnosis 3D virtual reality headset

Intervention Type DEVICE

3D experience to journey through a natural and therapeutic environment. Immersion is amplified by the realism of 3D environment, a soothing sound atmosphere and specific medical hypnosis.

Control

Standard of care : no hypnosis 3D virtual reality headset but a noise cancelling headphone

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Hypnosis 3D virtual reality headset

3D experience to journey through a natural and therapeutic environment. Immersion is amplified by the realism of 3D environment, a soothing sound atmosphere and specific medical hypnosis.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- Shock wave lithotripsy and outpatient surgery

Exclusion Criteria

* Epilepsy
* Deafness, Blindness
* Schizophrenia, Hallucinations
* No french-speaking
* Autistic
* Motion sickness
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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GAMIDA

UNKNOWN

Sponsor Role collaborator

Healthy Mind

INDUSTRY

Sponsor Role collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Darless Clausse, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital européen Geroges-Pompidou

Locations

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Assistance Publique Hôpitaux de Paris, Necker

Paris, , France

Site Status NOT_YET_RECRUITING

Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou

Paris, Île-de-France Region, France

Site Status RECRUITING

Countries

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France

Central Contacts

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Darless Clausse, MD

Role: CONTACT

331 56 09 54 11

Natacha Nohilé

Role: CONTACT

331 56 09 59 82

Facility Contacts

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Darless Clausse, MD

Role: primary

Darless CLAUSSE, MD

Role: primary

331 56 09 54 11

References

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Eijlers R, Utens EMWJ, Staals LM, de Nijs PFA, Berghmans JM, Wijnen RMH, Hillegers MHJ, Dierckx B, Legerstee JS. Systematic Review and Meta-analysis of Virtual Reality in Pediatrics: Effects on Pain and Anxiety. Anesth Analg. 2019 Nov;129(5):1344-1353. doi: 10.1213/ANE.0000000000004165.

Reference Type BACKGROUND
PMID: 31136330 (View on PubMed)

Scapin S, Echevarria-Guanilo ME, Boeira Fuculo Junior PR, Goncalves N, Rocha PK, Coimbra R. Virtual Reality in the treatment of burn patients: A systematic review. Burns. 2018 Sep;44(6):1403-1416. doi: 10.1016/j.burns.2017.11.002. Epub 2018 Feb 1.

Reference Type BACKGROUND
PMID: 29395400 (View on PubMed)

Chan E, Foster S, Sambell R, Leong P. Clinical efficacy of virtual reality for acute procedural pain management: A systematic review and meta-analysis. PLoS One. 2018 Jul 27;13(7):e0200987. doi: 10.1371/journal.pone.0200987. eCollection 2018.

Reference Type BACKGROUND
PMID: 30052655 (View on PubMed)

Other Identifiers

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IDRCB 2020-A02052-37

Identifier Type: OTHER

Identifier Source: secondary_id

APHP200879

Identifier Type: -

Identifier Source: org_study_id

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