Clinical Analysis of a Novel Flexor Tendon Repair Technique

NCT ID: NCT07068880

Last Updated: 2025-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

128 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-06-18

Study Completion Date

2027-07-31

Brief Summary

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The purpose of the research study is to determine the efficacy and efficiency of two tendon repair techniques: the CoNextions tendon repair device vs a standard of care, L-O (Lew-Omar), suture repair technique. The investigators will also determine if there are similar or different rates of complications and failures via both objective and subjective measures.

Detailed Description

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To determine the tendon failure/rupture rate of two tendon repair techniques: the CoNextions tendon repair device vs a standard of care suture repair technique. The investigators will determine if there are similar or different rates of complications and failures (both intraoperatively and at 2-week, 6-week, 3-month, and 6-month post-operative intervals).

Conditions

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Flexor Tendon Laceration

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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repair with the CoNextions tendon repair device

No interventions assigned to this group

repair with a "standard of care" repair technique known as the Lew-Omar (LO) technique

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Study subjects aged 22 and older.
* Subjects who sustained a Zone 2-5 flexor tendon lacerations

Exclusion Criteria

* Subjects under the age of 22 at the time of consent
* Subjects who sustained a Zone 1 flexor tendon injury
* Subjects who have had previous surgical procedures on the injured upper extremity.
* Subjects who have metal allergies
* Ischemia, blood supply compromise, and/or inadequate wound coverage
* Prior or current infections at or near the implant site
* Conditions which tend to limit the patient's ability or willingness to restrict activities or follow directions during the healing period
* Foreign-body sensitivity
* The physical contact of the CoNextions TR Tendon Repair System with metal implants made of anything other than the implant grade of stainless steel, such as titanium, titanium alloys, cobalt chromium, or other dissimilar metals
* Surgical procedures other than for the following indication: digital flexor tendons, digital extensor tendons proximal to the metacarpophalangeal joints (Zones 6-8)
* Tendon size or surgical site access outside of specified range (Tendon Width (3.0-9.0 mm), Tendon Thickness (1.5-4.0 mm), Minimum Surgical Site Access (20 mm \[10mm/side\]) for the CoNextions TR Tendon Repair System
Minimum Eligible Age

22 Years

Maximum Eligible Age

88 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Brett Lewellyn

OTHER

Sponsor Role lead

Responsible Party

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Brett Lewellyn

Chief Hand & Upper Extremity Surgery

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Orlando Health

Orlando, Florida, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Brett Lewellyn, MD

Role: CONTACT

321-843-5851

Facility Contacts

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Brett Lewellyn, MD

Role: primary

321-843-5851

Other Identifiers

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23.184.09

Identifier Type: -

Identifier Source: org_study_id

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