Is Pericapsular Nerve Group Block Better Than Interscalene Nerve Block Regarding Effect on Hand Movement in Shoulder Scope Surgeries?

NCT ID: NCT07057947

Last Updated: 2025-07-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-25

Study Completion Date

2025-12-31

Brief Summary

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The goal of this clinical trial is to learn if pericapsular nerve group block (PENG) in shoulder scope surgery provides adequate analgesia with less affection of muscle power compared to interscalene block. The main questions it aims to answer are:

Does PENG block provide analgesia similar to interscalene block? Does PENG block have less or no effect on muscle power compared to interscalene block? Researchers will compare PENG block with interscalene block

Participants will:

Receive either PENG or interscalene block before shoulder scope surgery Be evaluated for their motor power after receiving the block and after the surgery Be evaluated for pain after the surgery

Detailed Description

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Conditions

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Shoulder Arthroscopic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Group P

This arm will receive PENG block

Group Type ACTIVE_COMPARATOR

Pericapsular Nerve Group (PENG) Block

Intervention Type PROCEDURE

Injection of local anesthetic between deltoid muscle and subcapsularis tendon

Acuson X300 ultrasound,Siemens medical solution INC, Germany

Intervention Type DEVICE

high frequency linear probe

Group I

This arm will receive interscalene block

Group Type ACTIVE_COMPARATOR

Interscalene Nerve Block

Intervention Type PROCEDURE

Injection of local anesthetic between anterior and middle scalene muscles around the roots of brachial plexus

Acuson X300 ultrasound,Siemens medical solution INC, Germany

Intervention Type DEVICE

high frequency linear probe

Interventions

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Pericapsular Nerve Group (PENG) Block

Injection of local anesthetic between deltoid muscle and subcapsularis tendon

Intervention Type PROCEDURE

Interscalene Nerve Block

Injection of local anesthetic between anterior and middle scalene muscles around the roots of brachial plexus

Intervention Type PROCEDURE

Acuson X300 ultrasound,Siemens medical solution INC, Germany

high frequency linear probe

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult patients of the specified age range
* Any gender
* American Society of Anaesthesiologists physical status grades 1 and 2
* Body mass index less than 35
* Duration of surgery between 90 to 120 minutes

Exclusion Criteria

* American Society of Anaesthesiologists physical status grades 3 and 4
* Allergy to local anesthetics
* Coagulation disorder (INR \>1.2, Platelets \<100,000), or recent intake of clopidogrel or warfarin within 1 week
* Active infection at site of injection
Minimum Eligible Age

22 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sherin Refaat

OTHER

Sponsor Role lead

Responsible Party

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Sherin Refaat

Dr. Sherine Refaat Mahmoud, Assistant Professor of anesthesiology, surgical ICU and pain management

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Cairo University

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Research Ethics Committee

Role: CONTACT

+201112137888

Facility Contacts

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Bassem R Mansour, MSc

Role: primary

+201222722475

References

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Mosaffa F, Taheri M, Manafi Rasi A, Samadpour H, Memary E, Mirkheshti A. Comparison of pericapsular nerve group (PENG) block with fascia iliaca compartment block (FICB) for pain control in hip fractures: A double-blind prospective randomized controlled clinical trial. Orthop Traumatol Surg Res. 2022 Feb;108(1):103135. doi: 10.1016/j.otsr.2021.103135. Epub 2021 Oct 29.

Reference Type BACKGROUND
PMID: 34715388 (View on PubMed)

Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.

Reference Type BACKGROUND
PMID: 30063657 (View on PubMed)

Kupeli I, Yazici Kara M. Anesthesia or analgesia? New block for shoulder surgery: pericapsular nerve group block. Braz J Anesthesiol. 2022 Sep-Oct;72(5):669-672. doi: 10.1016/j.bjane.2021.05.009. Epub 2021 Jun 9.

Reference Type BACKGROUND
PMID: 34118263 (View on PubMed)

Hussain N, Goldar G, Ragina N, Banfield L, Laffey JG, Abdallah FW. Suprascapular and Interscalene Nerve Block for Shoulder Surgery: A Systematic Review and Meta-analysis. Anesthesiology. 2017 Dec;127(6):998-1013. doi: 10.1097/ALN.0000000000001894.

Reference Type BACKGROUND
PMID: 28968280 (View on PubMed)

Stasiowski M, Zuber M, Marciniak R, Kolny M, Chabierska E, Jalowiecki P, Pluta A, Missir A. Risk factors for the development of Horner's syndrome following interscalene brachial plexus block using ropivacaine for shoulder arthroscopy: a randomised trial. Anaesthesiol Intensive Ther. 2018;50(3):215-220. doi: 10.5603/AIT.a2018.0013. Epub 2018 Jun 22.

Reference Type BACKGROUND
PMID: 29931665 (View on PubMed)

Bergmann L, Martini S, Kesselmeier M, Armbruster W, Notheisen T, Adamzik M, Eichholz R. Phrenic nerve block caused by interscalene brachial plexus block: breathing effects of different sites of injection. BMC Anesthesiol. 2016 Jul 29;16(1):45. doi: 10.1186/s12871-016-0218-x.

Reference Type BACKGROUND
PMID: 27473162 (View on PubMed)

Paul RW, Szukics PF, Brutico J, Tjoumakaris FP, Freedman KB. Postoperative Multimodal Pain Management and Opioid Consumption in Arthroscopy Clinical Trials: A Systematic Review. Arthrosc Sports Med Rehabil. 2021 Dec 17;4(2):e721-e746. doi: 10.1016/j.asmr.2021.09.011. eCollection 2022 Apr.

Reference Type BACKGROUND
PMID: 35494281 (View on PubMed)

Guity MR, Sobhani Eraghi A, Hosseini-Baharanchi FS. Early postoperative pain as a risk factor of shoulder stiffness after arthroscopic rotator cuff repair. J Orthop Traumatol. 2021 Jun 26;22(1):25. doi: 10.1186/s10195-021-00585-9.

Reference Type BACKGROUND
PMID: 34173872 (View on PubMed)

Calvo E, Torres MD, Morcillo D, Leal V. Rotator cuff repair is more painful than other arthroscopic shoulder procedures. Arch Orthop Trauma Surg. 2019 May;139(5):669-674. doi: 10.1007/s00402-018-3100-0. Epub 2018 Dec 17.

Reference Type BACKGROUND
PMID: 30560289 (View on PubMed)

Zong LZ, Duan MM, Yuan WW, Lu HD. Efficacy of shoulder arthroscopic surgery for the treatment of rotator cuff injury: A protocol of systematic review and meta-analysis. Medicine (Baltimore). 2020 Jun 26;99(26):e20591. doi: 10.1097/MD.0000000000020591.

Reference Type BACKGROUND
PMID: 32590734 (View on PubMed)

Farmer KW, Wright TW. Shoulder arthroscopy: the basics. J Hand Surg Am. 2015 Apr;40(4):817-21. doi: 10.1016/j.jhsa.2015.01.002. Epub 2015 Feb 26.

Reference Type BACKGROUND
PMID: 25726045 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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MD-323-2024

Identifier Type: -

Identifier Source: org_study_id

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