The Effects of Artificial Air Negative Ions on High-Altitude Acclimatization, Serum HIF1, and PWC170 Index
NCT ID: NCT07056751
Last Updated: 2025-07-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2022-05-01
2024-11-11
Brief Summary
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Detailed Description
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Methods: Sixty healthy adults were randomly divided into two groups: an air negative ion intervention group (observation group) of 30 participants and a non-air negative ion intervention group (control group) of 30 participants. Air negative ion intervention was conducted one week before entering high-altitude areas, lasting for 8 hours each day. Before entering high-altitude areas, measurements were taken for height, weight, blood pressure, heart rate, routine blood tests, routine urine tests, biochemical profiles, blood oxygen saturation, and HIF1 (hypoxia-inducible factor 1). One week after entering high-altitude areas, the above indicators were retested, and the PWC170 index was calculated to evaluate changes in endurance during high-altitude activities.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Air negative ion intervention study
Arm 1: observation group (air negative ion intervention group) consisting of 30 individuals
Air negative ion intervention study
The observation group received air negative ion intervention every night for one week before entering the plateau (from 22:00 to 06:00). Before entering the plateau, they were in Putian City, China, where the temperature was about 28°C, humidity was about 68%, and the concentration of negative ions was approximately 800/cm³. The air negative ion converter used was the Mi Energy ET-21 model from RELTEC Medical Devices Corporation. Air negative and positive ion concentrations were measured using an ion detector (NKMH-103, HOKUTO, Japan) to ensure that each participant's room had a negative ion concentration of around 100,000/cm³.
No air negative ion intervention
Arm 2: control group (no air negative ion intervention group) consisting of 30 individuals
No air negative ion intervention
No air negative ion intervention
Interventions
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Air negative ion intervention study
The observation group received air negative ion intervention every night for one week before entering the plateau (from 22:00 to 06:00). Before entering the plateau, they were in Putian City, China, where the temperature was about 28°C, humidity was about 68%, and the concentration of negative ions was approximately 800/cm³. The air negative ion converter used was the Mi Energy ET-21 model from RELTEC Medical Devices Corporation. Air negative and positive ion concentrations were measured using an ion detector (NKMH-103, HOKUTO, Japan) to ensure that each participant's room had a negative ion concentration of around 100,000/cm³.
No air negative ion intervention
No air negative ion intervention
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
30 Years
MALE
Yes
Sponsors
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The First Hospital of Putian City, Putian, Fujian
OTHER_GOV
Responsible Party
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Zhizhong Chen
Doctor
Locations
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The Ethics Committee of Putian 95 Hospital
Putian, Fujian, China
Countries
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Other Identifiers
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FirstHPCF
Identifier Type: -
Identifier Source: org_study_id
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