Clinical Predictors of Capillary Refill Time and Their Association With Triage Categories

NCT ID: NCT07054151

Last Updated: 2025-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

313 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-01

Study Completion Date

2024-09-30

Brief Summary

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This observational study aims to determine the correlation between capillary refill time (CRT) and vital parameters in patients presenting to the emergency department.

It explores whether CRT is associated with triage categories and vital signs in non-traumatic patients, including oxygen saturation (SpO₂), heart rate, systolic and diastolic blood pressure, body temperature, forearm temperature, and respiratory rate.

Patients admitted to the emergency department of a training and research hospital were assigned triage codes (green, yellow, red). Their CRT was measured three times, and vital signs were recorded accordingly.

Detailed Description

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In the initial evaluation, patients admitted to the emergency department were assigned a triage color code, categorized as green, yellow, or red. In the color-coding system employed, green was designated as low urgency, yellow as medium urgency, and red as urgent. The allocation of triage codes is the responsibility of nurses who have undergone the requisite training. Following the completion of the assigned task, the emergency specialist proceeded to meticulously record a series of physiological parameters. These parameters included the CRT (in seconds), the percentage of oxygen saturation in the blood (SpO2%), the heart rate (in minutes), the systolic and diastolic blood pressure (in mmHg), the body temperature (in degrees Celsius), the forearm temperature measured at the CRT, and the respiratory rate (in minutes). CRT was evaluated three times for each patient, and the mean of these values was recorded as the CRT.

Conditions

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Triage Emergency Medical Services Vital Signs Monitoring Hypoperfusion Hemodynamic Instability

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Non-traumatic patients admitted to the emergency department of Izmir Democracy University Buca Seyfi

No clinical intervention (observational study only)

Intervention Type OTHER

This is an observational study. No experimental or clinical intervention was applied. Only non-invasive data collection such as capillary refill time and vital sign measurements was performed.

Interventions

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No clinical intervention (observational study only)

This is an observational study. No experimental or clinical intervention was applied. Only non-invasive data collection such as capillary refill time and vital sign measurements was performed.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* individuals over the age of 18 years who consented to participate in the study

Exclusion Criteria

* The presence of pregnancy
* Multiple traumas resulting in hypovolemia
* The absence of fingers or limbs
* The utilization of vasopressors or inotropic pharmacological agents
* The existence of peripheral arterial disease
* The presence of nail polish or fake nails
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Izmir Democracy University

OTHER

Sponsor Role lead

Responsible Party

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Zeynep Sofuoglu

Assoc. Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Aysel Başer, Assoc.Prof.

Role: STUDY_DIRECTOR

Izmir Democracy University, Medical Faculty

Locations

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Buca Training and Research Hospital, Emergency Deaprtment

Izmir, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Adhikari S. Available at: www.jgpeman.com, eISSN: 2363-1168 28 SHORT REVIEW: CAPILLARY REFILLL VS SERUM LACTATE IN SEPTIC. Vol. 7, SHOCK Journal of General Practice and Emergency Medicine of Nepal. 2018.

Reference Type BACKGROUND

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Reference Type BACKGROUND
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Baker AH, Mazandi VM, Norton JS, Melendez E. Emergency Department Sepsis Triage Scoring Tool Elements Associated With Hypotension Within 24 Hours in Children With Fever and Tachycardia. Pediatr Emerg Care. 2024 Sep 1;40(9):644-649. doi: 10.1097/PEC.0000000000003153. Epub 2024 Mar 13.

Reference Type BACKGROUND
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Sheridan DC, Cloutier R, Kibler A, Hansen ML. Cutting-Edge Technology for Rapid Bedside Assessment of Capillary Refill Time for Early Diagnosis and Resuscitation of Sepsis. Front Med (Lausanne). 2020 Dec 21;7:612303. doi: 10.3389/fmed.2020.612303. eCollection 2020.

Reference Type BACKGROUND
PMID: 33425956 (View on PubMed)

Jacquet-Lagreze M, Bouhamri N, Portran P, Schweizer R, Baudin F, Lilot M, Fornier W, Fellahi JL. Capillary refill time variation induced by passive leg raising predicts capillary refill time response to volume expansion. Crit Care. 2019 Aug 16;23(1):281. doi: 10.1186/s13054-019-2560-0.

Reference Type BACKGROUND
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Reference Type BACKGROUND
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Reference Type BACKGROUND

Sansone CM, Prendin F, Giordano G, Casati P, Destrebecq A, Terzoni S. Relationship between Capillary Refill Time at Triage and Abnormal Clinical Condition: A Prospective Study. Open Nurs J. 2017 Jul 26;11:84-90. doi: 10.2174/1874434601711010084. eCollection 2017.

Reference Type BACKGROUND
PMID: 28839512 (View on PubMed)

Schriger DL, Baraff L. Defining normal capillary refill: variation with age, sex, and temperature. Ann Emerg Med. 1988 Sep;17(9):932-5. doi: 10.1016/s0196-0644(88)80675-9.

Reference Type BACKGROUND
PMID: 3415066 (View on PubMed)

Jacquet-Lagreze M, Wiart C, Schweizer R, Didier L, Ruste M, Coutrot M, Legrand M, Baudin F, Javouhey E, Depret F, Fellahi JL. Capillary refill time for the management of acute circulatory failure: a survey among pediatric and adult intensivists. BMC Emerg Med. 2022 Jul 18;22(1):131. doi: 10.1186/s12873-022-00681-x.

Reference Type BACKGROUND
PMID: 35850662 (View on PubMed)

Lewin J, Maconochie I. Capillary refill time in adults. Emerg Med J. 2008 Jun;25(6):325-6. doi: 10.1136/emj.2007.055244. No abstract available.

Reference Type BACKGROUND
PMID: 18499809 (View on PubMed)

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Reference Type BACKGROUND

Van der Mullen J, Wise R, Vermeulen G, Moonen PJ, Malbrain MLNG. Assessment of hypovolaemia in the critically ill. Anaesthesiol Intensive Ther. 2018;50(2):141-149. doi: 10.5603/AIT.a2017.0077. Epub 2017 Nov 28.

Reference Type BACKGROUND
PMID: 29182211 (View on PubMed)

McGuire D, Gotlib A, King J. Capillary Refill Time. 2023 Apr 23. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK557753/

Reference Type BACKGROUND
PMID: 32491685 (View on PubMed)

Champion HR, Sacco WJ, Hannan DS, Lepper RL, Atzinger ES, Copes WS, Prall RH. Assessment of injury severity: the triage index. Crit Care Med. 1980 Apr;8(4):201-8. doi: 10.1097/00003246-198004000-00001.

Reference Type BACKGROUND
PMID: 7357873 (View on PubMed)

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Reference Type BACKGROUND
PMID: 7273818 (View on PubMed)

BEECHER HK, SIMEONE FA, et al. The internal state of the severely wounded man on entry to the most forward hospital. Surgery. 1947 Oct;22(4):672-711. No abstract available.

Reference Type BACKGROUND
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Pickard A, Karlen W, Ansermino JM. Capillary refill time: is it still a useful clinical sign? Anesth Analg. 2011 Jul;113(1):120-3. doi: 10.1213/ANE.0b013e31821569f9. Epub 2011 Apr 25.

Reference Type BACKGROUND
PMID: 21519051 (View on PubMed)

Related Links

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Other Identifiers

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IzmirDemocracy

Identifier Type: -

Identifier Source: org_study_id

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