Contribution of SuPAR for Patients in a Situation of Uncertainty Downstream of Emergencies

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

202 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-10

Study Completion Date

2022-04-18

Brief Summary

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In this study, the investigators will investigate the relationship between the blood level of SuPAR at admission to the emergency department of the Clermont-Ferrand University Hospital, and the outcome of patients after their hospitalization in a short stay unit.

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Detailed Description

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SuPAR (Soluble urokinase Plasminogen Activator Receptor) is a non-specific prognostic blood biomarker related to inflammation. An elevated SuPAR value reflects significant chronic inflammation and predicts a risk of negative outcome and even short-term mortality (intra-hospital, 30 days, 90 days). Conversely, a low SuPAR value is a strong indicator of good prognosis and low risk of readmission. It is therefore of interest to know a patient's SuPAR blood level to enable the clinician to decide whether the patient should be admitted or discharged. SuPAR has been shown to be the best prognostic marker associated with the presence and progression of disease and risk of mortality. The use of SuPAR in clinical routine adds significant complementary information to the standard Early Warning Score assessment and to the classical parameters such as CRP, PCT, Lactate, ALT, Bilirubin, and CBC in the pre-admission of acute patients.

Patients admitted to the emergency department will receive their usual management. We will test the added value of the SuPAR assay in the prognosis of patients' outcome at discharge.

Conditions

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Emergencies Disease In-hospital Observation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Experimental

Retrospective analysis of the correlation between SuPAR measurement and patient outcome after hospitalization

blood supar measurement

Intervention Type OTHER

The supar values will be measured afterwards on the tube bottoms of the patients included in the study from their usual collection

Interventions

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blood supar measurement

The supar values will be measured afterwards on the tube bottoms of the patients included in the study from their usual collection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient, male or female, over 18 years old
* Admitted to the emergency department of the Clermont-Ferrand University Hospital for a medical reason,
* Classified as FRENCH II or III by the nurse organizer of the reception management
* Necessity of clinical observation in the Short Term Hospitalization Unit for final orientation decision
* Requires a blood test upon arrival in the emergency department
* Able to give informed non-opposition to participate in the research.
* Affiliation to a Social Security system

Exclusion Criteria

* Patient under guardianship or curatorship
* Pregnant and breast feeding woman
* Patient admitted for psychiatric pathology
* Patient with a limitation of therapeutics
* Refusal to participate
* Patient hospitalized because of a particular social context

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No