The Advancing Dynamic And Personalized Training Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

1500 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-20

Study Completion Date

2027-06-30

Brief Summary

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This study aims to enhance the Healthy Minds Program (HMP) app by developing and testing a personalized, data-driven approach to optimize long-term well-being. 1100 participants will be enrolled and on study for up to 4 months (4 week intervention plus 3 month follow-up).

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Detailed Description

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Participants will be randomly assigned to various training conditions that vary across six factors. Each of the six factors is binary ("yes" vs. "no"), and for each factor there is a 50 percent probability of assignment to either level.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no)

Participants will take surveys at baseline, weekly through the 4-week intervention, and 3-month follow-up.

Conditions

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Well-Being, Psychological

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Participants are randomized to six different binary conditions. The investigators plan to collapse the groups for analysis, for example, combining participants with or without the introduction videos, regardless of their other assigned conditions.

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Introduction Video to HMP app

All participants are randomized to this condition (Yes or No)

Group Type EXPERIMENTAL

Healthy Minds Program (HMP) app

Intervention Type OTHER

All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no

Introduction Video to Training Modules

All participants are randomized to this condition (Yes or No)

Group Type EXPERIMENTAL

Healthy Minds Program (HMP) app

Intervention Type OTHER

All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no

Module Order based on ACIP Score

All participants are randomized to this condition (Highest score first or Lowest score first)

Group Type EXPERIMENTAL

Healthy Minds Program (HMP) app

Intervention Type OTHER

All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no

Practice-Nudging Test Messages

All participants are randomized to this condition (Yes or No)

Group Type EXPERIMENTAL

Healthy Minds Program (HMP) app

Intervention Type OTHER

All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no

Microsupport Messages During Intervention

All participants are randomized to this condition (Yes or No)

Group Type EXPERIMENTAL

Healthy Minds Program (HMP) app

Intervention Type OTHER

All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no

Microsupport Messages During Follow-Up

All participants are randomized to this condition (Yes or No)

Group Type EXPERIMENTAL

Healthy Minds Program (HMP) app

Intervention Type OTHER

All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no

Interventions

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Healthy Minds Program (HMP) app

All participants will complete baseline surveys, weekly questionnaires (for 4 weeks) through the HMP app intervention, and will be surveyed again at 3-months post-intervention. Participants are randomized to each of the following binary conditions.

1. Introduction video for the app (yes / no)
2. Introduction video for the training modules (yes / no)
3. Module order based on ACIP score (highest-first / lowest-first)
4. Practice-nudging text messages (yes / no)
5. Microsupport messages during the intervention period (yes / no)
6. Microsupport messages during the follow-up period (yes / no

Intervention Type OTHER

Other Intervention Names

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HMP app

Eligibility Criteria

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Inclusion Criteria

* Elevated symptoms of depression (PHQ-9 greater than or equal to 5)
* proficiency in English
* access to a smartphone and internet
* ability to receive text messages

Exclusion Criteria

* Prior experience with meditation
* Prior use of the Healthy Minds Program app
* History of psychosis or mania
* Plans to travel in the next six weeks
* Suicidal ideation or thoughts of self-harm indicated by PHQ-9 item 9 and BDI item 9
* Failure to select the correct code word mentioned in the welcome video
* Not a US citizen
* Non-permanent resident
* Self-identification as artificial intelligence (AI)
* Has a hearing impairment

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes