Cerebral Atherosclerosis Research With Positron Emission Tomography

NCT ID: NCT07041372

Last Updated: 2025-06-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

310 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-22

Study Completion Date

2029-08-31

Brief Summary

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The goal of this clinical trial is to learn if the application of fluorodeoxyglucose positron emission tomography can predict prognosis of stroke patients. The main questions it aims to answer are:

* Does FDG PET can predict future vascular events such as stroke recurrence, myocardial infarction or vascular death among stroke survivors?
* Does FDG PET can predict other important events such as fracture, dementia, bleeding, cancer and overall death among stroke survivors? Researchers will compare the FDG uptake in major organs - such as the amygdala, vertebrae, spleen, liver, internal carotid artery, visceral fat, and psoas muscle - between patients with and without the event of interest to determine whether FDG PET can predict the overall prognosis of stroke patients.

Participants will:

* Undergo whole-body FDG PET once their neurological status has stabilized after stroke.
* Complete questionnaires assessing stress and anxiety (PHQ-9 and PSS-10) on the same day.
* Maintain regular clinic visits for up to 24 months following the index stroke

Detailed Description

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Conditions

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Cerebral Infarction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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FDG-PET

The participants undergo whole-body FDG PET once their neurological status has stabilized after stroke.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* acute ischemic stroke patients who admitted within seven days after symptom onset

Exclusion Criteria

* Patients with unstable vital signs or neurological symptoms
* Patients with estimated glomerular filtration rate less than 30ml/min
* Patients with uncontrolled diabetes requiring persistent insulin injection
* During pregnancy or while breastfeeding
* Patients with impaired consent capacity
* Patients with diagnosed/treatment for dementia
* Patients undergoing treatment for malignant tumors or serious autoimmune diseases
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jeong-Min Kim

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Seoul National University Hospital

Seoul, Jong-ro Gu, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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CARPET

Identifier Type: -

Identifier Source: org_study_id

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