Accuracy of Venous Excess Ultrasound Score at Hospital Admission to Predict Acute Kidney Injury

NCT ID: NCT07040696

Last Updated: 2025-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-22

Study Completion Date

2025-12-31

Brief Summary

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To evaluate diagnostic accuracy of venous excess ultrasound score to predict acute kidney injury

Detailed Description

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Preeclampsia is a common health problem during pregnancy. such condition may result in serious consequences including acute kidney injury. researchers of this study aim to evaluate the ability of venous excess ultrasound score at hospital admission to predict acute kidney injury in preeclampsia with severe features

Conditions

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Preeclampsia Acute Kidney Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Preeclampsia with severe features

Features of severity will be defined according to American college of obstetric and gynacology guidelines

Venous excess ultrasound score (VEXUS)

Intervention Type DEVICE

Doppler examination of inferior vena cave, portal vein, hepatic vein, and intrarenal vein will be conducted by an experienced operator

Interventions

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Venous excess ultrasound score (VEXUS)

Doppler examination of inferior vena cave, portal vein, hepatic vein, and intrarenal vein will be conducted by an experienced operator

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* preeclampsia with severe features

Exclusion Criteria

* Patient refusal
* Preexisting renal impairment (defined as baseline serum creatinine \> 1.3 mg/dl)
* Inability to obtain adequate Doppler views
* Renal transplantation
* Previous need for renal replacement therapy
* Known peripheral vascular disease
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Mina Adolf Helmy

Lecturer of anesthesia

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cairo University

Cairo, Giza Governorate, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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cairo university

Role: CONTACT

+201275716942

Facility Contacts

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Cairo University

Role: primary

01275716942

References

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Viana-Rojas JA, Argaiz E, Robles-Ledesma M, Arias-Mendoza A, Najera-Rojas NA, Alonso-Bringas AP, De Los Rios-Arce LF, Armenta-Rodriguez J, Gopar-Nieto R, Briseno-De la Cruz JL, Gonzalez-Pacheco H, Sierra-Lara Martinez D, Gonzalez-Salido J, Lopez-Gil S, Araiza-Garaygordobil D. Venous excess ultrasound score and acute kidney injury in patients with acute coronary syndrome. Eur Heart J Acute Cardiovasc Care. 2023 Jul 7;12(7):413-419. doi: 10.1093/ehjacc/zuad048.

Reference Type BACKGROUND
PMID: 37154067 (View on PubMed)

Rola P, Miralles-Aguiar F, Argaiz E, Beaubien-Souligny W, Haycock K, Karimov T, Dinh VA, Spiegel R. Clinical applications of the venous excess ultrasound (VExUS) score: conceptual review and case series. Ultrasound J. 2021 Jun 19;13(1):32. doi: 10.1186/s13089-021-00232-8.

Reference Type BACKGROUND
PMID: 34146184 (View on PubMed)

Naqvi R, Hossain N, Butt S, Bhellar Z, Fatima E, Imtiaz S, Moosa PG, Abbas K, Jafri SB, Khan S. Efficacy of multiple Biomarkers: NGAL, KIM1, Cystatin C and IL18 in predicting pregnancy related acute kidney injury. Pak J Med Sci. 2023 Jan-Feb;39(1):34-40. doi: 10.12669/pjms.39.1.6930.

Reference Type BACKGROUND
PMID: 36694779 (View on PubMed)

Hassan M, Mayanja R, Ssalongo WGM, Robert N, Mark LH, Samson O, Muhindo R. Incidence and predictors of acute kidney injury among women with severe pre-eclampsia at Mbarara Regional Referral Hospital. BMC Nephrol. 2022 Nov 2;23(1):353. doi: 10.1186/s12882-022-02972-8.

Reference Type BACKGROUND
PMID: 36324072 (View on PubMed)

Other Identifiers

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VEXUS score in preeclampsia

Identifier Type: -

Identifier Source: org_study_id

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