Urinary NGAL Acute Kidney Injury After Stored Red Blood Cells Transfusion in Critically Ill Patients.

NCT ID: NCT03560921

Last Updated: 2018-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

147 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-06-02

Study Completion Date

2017-12-05

Brief Summary

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The study aims to explore the association of the novel urinary bio marker NGAL with the age of PRBCs(packed red blood cells) transfusion in critically ill patients.

Detailed Description

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The investigators will measure the urinary NGAL in all patients who received blood transfusion in the intensive care unit during the study period. The age of PRBCs transfusion will be correlated with the incidence of AKI. The rise of NGAL and serum creatinine will be used to diagnose AKI (Acute Kidney Injury).

Conditions

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Acute Kidney Injury Anemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Stored blood transfusion

measurement of urinary NGAL

urinary NGAL

Intervention Type DIAGNOSTIC_TEST

measurement urinary NGAL using the ARCHITECT technique

Fresh blood transfusion

measurement of urinary NGAL

urinary NGAL

Intervention Type DIAGNOSTIC_TEST

measurement urinary NGAL using the ARCHITECT technique

Interventions

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urinary NGAL

measurement urinary NGAL using the ARCHITECT technique

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Any patients admitted to the intensive care unit.

Exclusion Criteria

* patients who have established AKI at the time of recruitment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kasr El Aini Hospital

OTHER

Sponsor Role lead

Responsible Party

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Tarek Samy Abdelziz

Senior lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tarek Abdelaziz

Role: PRINCIPAL_INVESTIGATOR

faculty of medicine-Cairo University Hospitals

Locations

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Cairo university hospitals

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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KA-13115

Identifier Type: -

Identifier Source: org_study_id

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