Prevalence and Determinants of Migraine Among Headache Patients

NCT ID: NCT07038499

Last Updated: 2025-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

158 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-23

Study Completion Date

2025-10-31

Brief Summary

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Migraine is a prevalent and disabling neurological condition that often coexists with other health issues, such as hypertension and impaired physical, mental, and social functioning. Understanding the prevalence of migraine and its associations with these health domains can provide valuable insights into the broader impact of migraine on overall well-being. By focusing on patients at the Affiliated Hospital of Hebei University of Engineering in China, this study can identify specific health burdens within this population, inform integrated clinical management strategies, and support the development of targeted interventions to improve patient outcomes and quality of life.

Detailed Description

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Migraine is a common and disabling neurological disorder that poses a significant public health burden worldwide. In China, the estimated prevalence of migraine is approximately 9.3%, with higher rates reported among women and individuals of working age. Despite being one of the most prevalent types of primary headache disorders, migraine remains underdiagnosed and undertreated in many regions of China, partly due to limited awareness and access to specialized care. Concurrently, hypertension is highly prevalent in the Chinese adult population, with nearly one in four adults affected, making it a leading contributor to cardiovascular morbidity. Emerging evidence suggests a potential bidirectional relationship between migraine and hypertension, possibly linked through shared pathophysiological mechanisms such as endothelial dysfunction, autonomic dysregulation, and inflammatory pathways.

Moreover, migraine is often associated with detrimental effects on physical, mental, and social health, including impaired physical function, increased pain intensity, depression, anxiety, fatigue, sleep disturbances, and reduced ability to participate in social roles and activities. However, studies exploring these multidimensional impacts in Chinese clinical populations remain limited.

Therefore, this study aims to investigate the prevalence of migraine and its association with hypertension as well as physical, mental, and social health domains among headache patients at the Affiliated Hospital of Hebei University of Engineering, China.

Conditions

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Headache (Migraine)

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Participants are not assigned an intervention as part of the study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

• Patients diagnosed with headache according to the International Classification of Headache Disorders, 3rd Edition (ICHD-3).

Exclusion Criteria

* Patients with other major diseases or severe mental disorders;
* History of endocrine, immune, or nervous system diseases or other severe somatic diseases.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universiti Tunku Abdul Rahman

OTHER

Sponsor Role lead

Responsible Party

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Foo Chai Nien

Assiociate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Chai Nien Associate Professor, PhD

Role: PRINCIPAL_INVESTIGATOR

Universiti Tunku Abdul Rahman

Locations

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Affiliated Hospital of Hebei University of Engineering, China

Hebei, , China

Site Status

Countries

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China

Central Contacts

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Chai Nien Associate Professor, PhD

Role: CONTACT

+60123167252

Chai Nien Associate Professor, PhD

Role: CONTACT

Facility Contacts

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Yuping Student

Role: primary

Other Identifiers

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2024[k]-122

Identifier Type: OTHER

Identifier Source: secondary_id

2024[K]122

Identifier Type: -

Identifier Source: org_study_id

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