The Effect of Quadratus Lumborum (QL) Block on the Incidence of Chronic Neuropathic Pain After Retroperitoneal Laparoscopic Donor Nephrectomy: A Study on Neuroinflammation and Neurophysiology

NCT ID: NCT07037992

Last Updated: 2025-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-01

Study Completion Date

2025-12-31

Brief Summary

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To analyze the relationship of anterior subcostal quadratus lumborum (QL) block compared with control block on the incidence of chronic neuropathic pain at three months post-laparoscopic retroperitoneal living kidney donor.

Detailed Description

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Conditions

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Chronic Pain Living Kidney Donor Quadratus Lumborum Block Laparoscopic Donor Nephrectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Quadratus Lumborum Block

Group Type EXPERIMENTAL

injection of local anesthesia solution

Intervention Type DRUG

Injection of 30 mL local anesthetic solution bupivacaine 0.25%

Quadratus Lumborum Sham Block

Group Type PLACEBO_COMPARATOR

Injection of normal saline

Intervention Type DRUG

Injection of 30 mL normal saline Natrium Chloride (NaCl) 0.9%

Interventions

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injection of local anesthesia solution

Injection of 30 mL local anesthetic solution bupivacaine 0.25%

Intervention Type DRUG

Injection of normal saline

Injection of 30 mL normal saline Natrium Chloride (NaCl) 0.9%

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Living kidney donor candidate patients aged 18-65 years Patients with ASA physical status assessment 1-3 Patients are willing to be research subjects.

Exclusion Criteria

* The patient was known to have a history of chronic non-cancer pain and cancer pain.

The patient had a history of preoperative laparoscopic kidney donor surgery.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Indonesia University

OTHER

Sponsor Role lead

Responsible Party

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Raden Besthadi Sukmono

Anesthesiologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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RSUPN Cipto Mangunkusumo

Jakarta Pusat, Jakarta Special Capital Region, Indonesia

Site Status

Countries

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Indonesia

Central Contacts

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Raden B Sukmono

Role: CONTACT

+628129508625

Facility Contacts

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Raden B Sukmono

Role: primary

+62129508625

Other Identifiers

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QLChronicNeuropathicPostOpPain

Identifier Type: -

Identifier Source: org_study_id

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