Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Adrenalectomy

NCT ID: NCT03844477

Last Updated: 2019-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-16

Study Completion Date

2019-05-15

Brief Summary

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This prospective, randomized ,control study aims to compare the analgesic effect,quality of recovery, length of hospital stay ,et al. between single-injection QLB(quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.

Detailed Description

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Conditions

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Pain Management Nerve Block Laparoscopic Adrenalectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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single-injection QLB(quadratus lumborum block)

Single-injection of QLB with local anesthetic is given preoperatively

Group Type EXPERIMENTAL

single-injection QLB(quadratus lumborum block)

Intervention Type PROCEDURE

Inject 0.4ml/kg 0.5% ropivacaine between quadratus lumborum and psoas major without continuous local infusion

Device: Ultrasound Scanner The curved (C1-5) probe of Ultrasound Scanner is used for scan

Device: PAJUNK StimuLong Drug: single dose ropivacaine 0.4ml/kg 0.5% ropivacaine given immediately after the correct position of the tip of the needle has been verified.

Placebo control

Single-injection of QLB with NS is given preoperatively

Group Type PLACEBO_COMPARATOR

Placebo control

Intervention Type PROCEDURE

Inject 0.4ml/kg saline between quadratus lumborum and psoas major without continuous local infusion

Device: Ultrasound Scanner The curved (C1-5) probe of Ultrasound Scanner is used for scan

Device: PAJUNK StimuLong Drug: single dose 0.4ml/kg 0.9% NS. given immediately after the correct position of the tip of the needle has been verified.

Interventions

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single-injection QLB(quadratus lumborum block)

Inject 0.4ml/kg 0.5% ropivacaine between quadratus lumborum and psoas major without continuous local infusion

Device: Ultrasound Scanner The curved (C1-5) probe of Ultrasound Scanner is used for scan

Device: PAJUNK StimuLong Drug: single dose ropivacaine 0.4ml/kg 0.5% ropivacaine given immediately after the correct position of the tip of the needle has been verified.

Intervention Type PROCEDURE

Placebo control

Inject 0.4ml/kg saline between quadratus lumborum and psoas major without continuous local infusion

Device: Ultrasound Scanner The curved (C1-5) probe of Ultrasound Scanner is used for scan

Device: PAJUNK StimuLong Drug: single dose 0.4ml/kg 0.9% NS. given immediately after the correct position of the tip of the needle has been verified.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age 18-70 yrs
* American Society of Anesthesiologists physical statusⅠ-Ⅲ
* Undergo laparoscopic adrenalectomy
* Informed consent

Exclusion Criteria

* A known allergy to the drugs being used
* Coagulopathy, on anticoagulants
* Analgesics intake, history of substance abuse
* Participating in the investigation of another experimental agent
* Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

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Cui Xulei

Attending physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Xulei CUI, md

Role: PRINCIPAL_INVESTIGATOR

Peking Union Medical College Hospital

Locations

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Peking Union Medical College Hospital

Beijing, , China

Site Status

Countries

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China

Other Identifiers

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cuixulei6

Identifier Type: -

Identifier Source: org_study_id

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