Post-operative Analgesia Efficacy Using Ultrasound-guided Transmuscular Quadratus Lumborum Block Versus Ultrasound-guided Quadratus Lumborum Type II Block.

NCT ID: NCT03100994

Last Updated: 2017-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-28

Study Completion Date

2018-07-31

Brief Summary

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Post-operative analgesia efficacy using ultrasound-guided transmuscular quadratus lumborum block versus ultrasound-guided quadratus lumborum type II block

Detailed Description

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The Quadratus Lumborum (QL) Block is an ultrasound-guided technique described by Rafael Blanco in 2007. The nerves to the lower abdominal wall can be anesthetized by injecting local anesthetics between the quadratus lumborum muscle and latissimus dorsi muscle, which is called quadratus lumborum type II block. 〝 Transmuscular quadratus lumborum block demonstrates that injectate spreads over the posterior abdominal wall to the psoas major muscle and includes the upper branches of the lumbar plexus.〞described by Adhikary in 2016. However there are no published reports comparing the 2 techniques. In our study, compared of ultrasound-guided QL2-blocks with transmuscular quadratus lumborum block to investigate analgesic consumption, pain level, opioid related side effects and mobilization.

Conditions

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Nerve Block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

3 group: Group A: without intervention; Group B: Ultrasound-guided transmuscular quadratus lumborum block; Group C: Ultrasound-guided quadratus lumborum type II block
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Group A

without nerve block

Group Type NO_INTERVENTION

No interventions assigned to this group

Group B

Ultrasound guided transmuscular quadratus lumborum block with 0.125% bupivacaine 30ml

Group Type ACTIVE_COMPARATOR

Bupivacaine

Intervention Type DRUG

injecting anesthetics to different local

Ultrasound

Intervention Type DEVICE

Ultrasound guided nerve block

Group C

Ultrasound guided quadratus lumborum type 2 block with 0.125% bupivacaine 30ml

Group Type ACTIVE_COMPARATOR

Bupivacaine

Intervention Type DRUG

injecting anesthetics to different local

Ultrasound

Intervention Type DEVICE

Ultrasound guided nerve block

Interventions

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Bupivacaine

injecting anesthetics to different local

Intervention Type DRUG

Ultrasound

Ultrasound guided nerve block

Intervention Type DEVICE

Other Intervention Names

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Marcaine Philp

Eligibility Criteria

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Inclusion Criteria

* American Society of Anesthesiologists classification (ASA) 1\~3
* adequate communication skills
* Body mass index \< 32

Exclusion Criteria

chronic pain neurological illness/ neuropathy contraindication against local anesthetics
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tri-Service General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Wu Hsuan-Cheng

Principal Investigator, Department of Anesthesiology,Tri-ServiceGeneralHospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hsuan-Cheng Wu

Role: PRINCIPAL_INVESTIGATOR

Tri-Service General Hospital

Locations

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Tri-Service General Hospital

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Hsuan-Cheng Wu, Dr.

Role: CONTACT

Facility Contacts

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Shih-Hua Lin, PhD.

Role: primary

References

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Adhikary SD, El-Boghdadly K, Nasralah Z, Sarwani N, Nixon AM, Chin KJ. A radiologic and anatomic assessment of injectate spread following transmuscular quadratus lumborum block in cadavers. Anaesthesia. 2017 Jan;72(1):73-79. doi: 10.1111/anae.13647. Epub 2016 Oct 12.

Reference Type RESULT
PMID: 27730633 (View on PubMed)

Blanco R, Ansari T, Riad W, Shetty N. Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Pain After Cesarean Delivery: A Randomized Controlled Trial. Reg Anesth Pain Med. 2016 Nov/Dec;41(6):757-762. doi: 10.1097/AAP.0000000000000495.

Reference Type RESULT
PMID: 27755488 (View on PubMed)

Other Identifiers

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1-105-05-157

Identifier Type: -

Identifier Source: org_study_id

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