Treatment Outcome in Patients After eCPR

NCT ID: NCT07031466

Last Updated: 2025-12-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

74 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2025-11-30

Brief Summary

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This study consists of two parts - retrospective and prospective. The aim of this study is to assess the quality of life in bio-psycho-social dimensions in patients after eCPR (extracorporeal cardiopulmonary resuscitation), in relation to their neurological outcome after the end of treatment and discharge from the Ostrava University Hospital (FNO). The study will focus on patients who underwent extracorporeal membrane oxygenation (ECMO) support after out-of-hospital cardiac arrest (OHCA) in the years 2022-2024.

Detailed Description

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Retrospective study Quantitative evaluation using data analysis from documentation. Patients on ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024 will be evaluated based on data from the documentation. Analysis of data from the documentation of selected patients will be performed, evaluating demographic data, comorbidities, duration of ECMO support, mortality, Cerebral Performance Category (CPC) score 30 days after CPR.

Prospective study Quantitative assessment using validated questionnaire tools Patients connected to ECMO after OHCA in the period 1. 1. 2022 - 31. 12. 2024, in whom a CPC score \>3 was detected after the 30th day from cardiac arrest and who were discharged from the FNO. As part of patient dispensary, these patients are electively invited to the PICS outpatient clinic in the FNO Ostrava. Individual interviews (filling out questionnaires) will be performed after obtaining informed consent in the Post-Intensive Care Syndrome (PICS) outpatient clinic at the University Hospital Ostrava, or telephone interviews conducted by the attending physician.

Conditions

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Cardiac Arrest (CA)

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Retrospective eCPR group

Retrospective analysis of eCPR patients

Retrospective analysis of assigned treatment

Intervention Type OTHER

Retrospective analysis of assigned treatment will be performed

Prospective eCPR group

Prospective analysis of eCPR patients

Hospital Anxiety and Depression (HADS)

Intervention Type OTHER

Hospital Anxiety and Depression will be assessed using the HADS (Hospital Anxiety and Depression Scale)

Quality of Life (SF-36)

Intervention Type OTHER

The quality of life will be assessed using the SF-36 (Short-Form Health Subject Questionnaire).

Quality of Life (EQ-5D)

Intervention Type OTHER

The quality of life will be assessed using the EQ-5D (European Quality of Life Questionnaire)

Interventions

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Hospital Anxiety and Depression (HADS)

Hospital Anxiety and Depression will be assessed using the HADS (Hospital Anxiety and Depression Scale)

Intervention Type OTHER

Quality of Life (SF-36)

The quality of life will be assessed using the SF-36 (Short-Form Health Subject Questionnaire).

Intervention Type OTHER

Quality of Life (EQ-5D)

The quality of life will be assessed using the EQ-5D (European Quality of Life Questionnaire)

Intervention Type OTHER

Retrospective analysis of assigned treatment

Retrospective analysis of assigned treatment will be performed

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient who underwent eCPR after OHCA at University Hospital Ostrava
* Hospitalised in the period from 1. 1. 2022 to 31. 12. 2024
* Ability to undergo an interview personally or a family member able to provide information
* Signed informed consent

Exclusion Criteria

* Language barrier
* Acute serious mental or somatic disease making the interview not feasible
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Ostrava

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michaela Lišková, Bc.

Role: PRINCIPAL_INVESTIGATOR

University of Ostrava

Locations

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University of Ostrava

Ostrava, Moravian-Silesian Region, Czechia

Site Status

University Hospital Ostrava

Ostrava, Moravian-Silesian Region, Czechia

Site Status

Countries

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Czechia

Other Identifiers

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FNO-KARIM-eCPR

Identifier Type: -

Identifier Source: org_study_id

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