Neural Mobilization Exercises on Pain and Central Sensitization

NCT ID: NCT07027059

Last Updated: 2025-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-01

Study Completion Date

2026-05-31

Brief Summary

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This study aims to investigate the effects of neural mobilization exercises on central sensitization and pain characteristics in individuals with lateral epicondylitis. Enrolled participants will be randomly assigned to two groups. One group will receive routine exercises and ESWT treatment, while the other group will receive neural mobilization exercises in addition to routine exercises and ESWT treatment.

Detailed Description

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This study aims to investigate the effects of neural mobilization exercises on central sensitization and pain characteristics in individuals with lateral epicondylitis. Enrolled participants will be randomly assigned to two groups. One group will receive routine exercises and ESWT treatment, while the other group will receive neural mobilization exercises in addition to routine exercises and ESWT treatment.

Median nerve mobilizations will be implemented as the neural mobilization exercises. All groups will receive two sessions per week and complete the process in four weeks; therefore, they will have received a total of eight sessions by the end of the study. Routine exercises and median nerve mobilizations will be implemented in every session (twice a week), while ESWT will be implemented once a week.

Median nerve mobilizations will be administered in 5 sets, each consisting of 10 repetitions per session.

Before and after the sessions, subjective factors related to pain will be assessed using the Central Sensitization Scale and the Pain Catastrophizing Scale, as well as pressure pain threshold measurements.

Conditions

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Lateral Epicondylitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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mobilization

participants will receive additional median nerve mobilizations

Group Type EXPERIMENTAL

median nerve mobilization

Intervention Type BEHAVIORAL

An exercise to increase median nerve mobility by flexing and extending fingers, wrist, elbow, shoulder, and neck

routine exercises for lateral epicondylisits

Intervention Type BEHAVIORAL

eccentric strengthening exercises

control

participants will receive routine exercises

Group Type ACTIVE_COMPARATOR

routine exercises for lateral epicondylisits

Intervention Type BEHAVIORAL

eccentric strengthening exercises

Interventions

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median nerve mobilization

An exercise to increase median nerve mobility by flexing and extending fingers, wrist, elbow, shoulder, and neck

Intervention Type BEHAVIORAL

routine exercises for lateral epicondylisits

eccentric strengthening exercises

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of lateral epicondylitis
* 18-65 years old

Exclusion Criteria

Any other pathology, disease, condition, pain, surgery on the elbow, wrist, fingers, shoulder, or neck in the last year
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Izmir Katip Celebi University

OTHER

Sponsor Role lead

Responsible Party

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kevser kacmaz

research asisstant, phd

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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kevser sevik kacmaz, pt, phd

Role: PRINCIPAL_INVESTIGATOR

Izmir Katip Celebi University

Locations

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Izmir Katip Celebi University

Izmir, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Facility Contacts

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kevser kacmaz Kacmaz, PT, PhD

Role: primary

505-550-9879

References

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Coombes BK, Bisset L, Vicenzino B. Management of Lateral Elbow Tendinopathy: One Size Does Not Fit All. J Orthop Sports Phys Ther. 2015 Nov;45(11):938-49. doi: 10.2519/jospt.2015.5841. Epub 2015 Sep 17.

Reference Type BACKGROUND
PMID: 26381484 (View on PubMed)

Other Identifiers

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Lepicondilitis

Identifier Type: -

Identifier Source: org_study_id

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