T-prf Versus T-prf and Low-level Laser Stimulation on Bone Healing at Posterior Mandibular Fractures

NCT ID: NCT06970379

Last Updated: 2025-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-30

Study Completion Date

2025-01-21

Brief Summary

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Different types of grafting substances have been used in the recent decade to accelerate bone healing at large bony facial defects. PRF was one of the gold standard materials to be used until it was replaced by its successor T-PRF due to the PRF hazards of preparation. However, T-PRF- still can't stand alone in full bone enhancement procedure. Therefore, the combination with another bone bio-modulation technique, like Low-level Laser Therapy, is a must to approach the full advantage of bone healing. Aim: To compare between the effect of using T-PRF versus T-PRF with Low Level Laser stimulation on bone healing at posterior mandibular fractures

Detailed Description

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Conditions

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Posterior Mandibular Fractures

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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T-PRF

Group Type EXPERIMENTAL

T-PRF

Intervention Type OTHER

Patients received T-PRF placement at the fracture line.

T-PRF and LLLT

Group Type EXPERIMENTAL

T-PRF and Laser biomodulation

Intervention Type OTHER

Subjects underwent the process of bio-stimulation of the fracture line using low-level laser therapy. Wavelength \[λ\]: 660 nm, Power: 100 mW, Spot size \[Ø\]: 0.06 cm2, and for 60 seconds

Interventions

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T-PRF

Patients received T-PRF placement at the fracture line.

Intervention Type OTHER

T-PRF and Laser biomodulation

Subjects underwent the process of bio-stimulation of the fracture line using low-level laser therapy. Wavelength \[λ\]: 660 nm, Power: 100 mW, Spot size \[Ø\]: 0.06 cm2, and for 60 seconds

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients suffering from posterior mandibular fracture

Exclusion Criteria

* Patients with an untreated old Mandibular fracture.
* Patient with hematological diseases (thrombocytopenia, hemorrhagic disease, and diabetes).
* Comminuted fracture with bone loss.
* There is an infection at the fracture line.
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alexandria University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt

Alexandria, Azarita, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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0855-02/2024

Identifier Type: -

Identifier Source: org_study_id

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