Alveolar Ridge Preservation With Cortico-cancellous Porcine Bone
NCT ID: NCT06970184
Last Updated: 2025-05-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
22 participants
OBSERVATIONAL
2021-06-15
2025-06-01
Brief Summary
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Detailed Description
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Patients requiring the extraction of an hopeless tooth followed by ARP and subsequent implant placement are considered potentially eligible for the study.
At T0, Tooth extractions are performed trying to reduce the surgical trauma as possible. ARP is performed with 2 different combinations of a cortico-cancellous porcine bone with a thermogel (50:50 ratio, hand-mixed or 80:20 ratio, pre-mixed).
After 4 months of healing, patients undergo a radiographic examination before implant placement.
A T1, Implant site preparation is carried out using a trephine bur (to remove a core biopsy of the bone) followed by conventional osteotomy drills, and bone-level implants are placed. Bone samples are analyzed to evaluate new bone formation, presence of residual graft particles and marrow spaces.
Three months after placement, all implants are rehabilitated with screw-retained prosthetic crowns (T2).
Follow up is scheduled 1 year after prosthetic loading (T3).
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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ARP 50:50
Tooth extraction + ARP with collagenated porcine bone hand-mixed (ratio 50:50) with a thermogel
tooth extraction with alveolar ridge preservation
alveolar ridge preservation performed after tooth extraction
Implant placement
Implant placement
ARP 80:20
Tooth extraction + ARP with collagenated porcine bone pre-mixed (ratio 80:20) with a thermogel
tooth extraction with alveolar ridge preservation
alveolar ridge preservation performed after tooth extraction
Implant placement
Implant placement
Interventions
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tooth extraction with alveolar ridge preservation
alveolar ridge preservation performed after tooth extraction
Implant placement
Implant placement
Eligibility Criteria
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Inclusion Criteria
* Needing tooth extraction followed by ARP and implant-prosthetic rehabilitation
Exclusion Criteria
* uncontrolled periodontitis
* undergoing previous or actual treatment with medications/radiations potentially impairing hard and soft tissues healing
* women during pregnancy or breastfeeding
18 Years
ALL
No
Sponsors
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University of Pisa
OTHER
Responsible Party
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Antonio Barone
Full Professor
Locations
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U.O. Odontostomatologia e Chirurgia del Cavo Orale
Pisa, Italy, Italy
Countries
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Other Identifiers
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BONEISTO_ARP
Identifier Type: -
Identifier Source: org_study_id
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