Effect of Intravenous Low-Dose Ketamine Infusion With Intravenous Lignocaine Infusion on Post-Operative Pain in Patients Undergoing Laparoscopic Choleysystectomy Under General Anesthesia
NCT ID: NCT06964555
Last Updated: 2025-05-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
100 participants
INTERVENTIONAL
2024-01-01
2024-12-31
Brief Summary
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Sample Selection: Patients of both the gender of age at least 18 years, planned for elective LC with ASA grade I-II were included. Patients with obesity, history of alcohol consumptions, drug abusers, uncontrolled hypertension and diabetics, with chronic pain, allergic to study drugs, having neurological disorders, unable to understand pain scoring system and converted to open LC were excluded.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Group L
Just before the skin incision intravenous lignocaine was given.
Intravenous lignocaine
IV Lignocaine was given at the rate of 1 mg/kg/hr.
Group K
Just before the skin incision, intravenous ketamine was given
Intravenous Ketamine Infusions
Ketamine group received ketamine at 0.2mg/kg bolus intravenously followed by ketamine infusion at rate of 0.2mg/kg/hr throughout the surgery.
Interventions
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Intravenous Ketamine Infusions
Ketamine group received ketamine at 0.2mg/kg bolus intravenously followed by ketamine infusion at rate of 0.2mg/kg/hr throughout the surgery.
Intravenous lignocaine
IV Lignocaine was given at the rate of 1 mg/kg/hr.
Eligibility Criteria
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Inclusion Criteria
* Patients planned for elective LC
* Patients with ASA grade I-II were included.
Exclusion Criteria
* Patients with history of alcohol consumptions, uncontrolled hypertension and diabetics,
* Drug abusers
* Patients with chronic pain
* Patients allergic to study drugs
* Patients having neurological disorders or unable to understand pain scoring system
* Patients converted to open LC
18 Years
ALL
No
Sponsors
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Fazaia Ruth Pfau Medical College
OTHER
Responsible Party
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Syeda Hajrah Rehman
Principal Investigator
Locations
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Fazaia Ruth Pfau Medical College
Karachi, Sindh, Pakistan
Countries
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Other Identifiers
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FRPMC-IRB-2024-41
Identifier Type: -
Identifier Source: org_study_id
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