Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural Effusion
NCT ID: NCT06964321
Last Updated: 2025-05-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
66 participants
INTERVENTIONAL
2025-06-01
2026-08-01
Brief Summary
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It is a common symptom and accompanying presentation of metastatic disease. It Impacts up to 15% of all patients with cancer and is the most common in breast, lung, cancer, lymphoma, and gynaecological malignancies . There are 150,000 new cases of MPE in the United States yearly and 100,000 in Europe . Patients have an overall survival (OS) rate of 3-12 months after the initial diagnosis . Malignant pleural effusion (MPE) poses significant challenges in management, impacting patient quality of life and overall prognosis. Almost all radiological procedures can help diagnose pleural effusions . Thoracentesis is used as a diagnostic and therapeutic tool. The procedure has been modified with the addition of ultrasound, that is very functional for targeting certain anatomical areas of the pleura and finding an appropriate entry point . Three primary strategies are commonly employed: intercostal tube drainage, big tail catheter drainage, and ultrasound-guided aspiration. This study aims to evaluate these methods' efficacy, safety, and outcomes. To compare intercostal tube drainage, big tail catheter drainage, and ultrasound-guided aspiration in managing massive malignant pleural effusion (MPE).
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Group A
intercostal tube drainage in managing massive malignant pleural effusion (MPE).
intercostal tube drainage
intercostal tube drainage in managing massive malignant pleural effusion (MPE).
Group B
big tail catheter drainage in managing massive malignant pleural effusion (MPE).
big tail catheter drainage
big tail catheter drainage in managing massive malignant pleural effusion (MPE).
Group C
ultrasound-guided aspiration in managing massive malignant pleural effusion (MPE).
ultrasound-guided aspiration
ultrasound-guided aspiration in managing massive malignant pleural effusion (MPE).
Interventions
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intercostal tube drainage
intercostal tube drainage in managing massive malignant pleural effusion (MPE).
big tail catheter drainage
big tail catheter drainage in managing massive malignant pleural effusion (MPE).
ultrasound-guided aspiration
ultrasound-guided aspiration in managing massive malignant pleural effusion (MPE).
Eligibility Criteria
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Inclusion Criteria
* Patients diagnosed with massive malignant pleural effusion (MPE) requiring intervention.
Exclusion Criteria
* Patients with non-malignant causes of pleural effusion.
18 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Mark Badrat William Mansour
residant doctor
Other Identifiers
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IT drainage-pigtail-US Aspirat
Identifier Type: -
Identifier Source: org_study_id
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