Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)
NCT ID: NCT05872126
Last Updated: 2023-05-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
60 participants
INTERVENTIONAL
2023-04-01
2025-04-30
Brief Summary
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Management of symptomatic malignant pleural effusion remains to be a point of debate. Data available from literature shows conflicting results lacking high quality evidence which necsscitates further research work. Options differs to include chemical pleurodesis using medical or surgical talc poudrage or slurry. Surgical intervention with abrasion pleurodesis or pleurectomy using VATS approach has been used in many studies. Using indwelling pleural catheters (IPCs) has also proved comparable efficacy at many clinical trials. In this study we want to help answering this question so that we can add to the current knowledge aiming to offer the best care for those patients
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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VATS surgical pleurodesis
Patients in whom we use VATS-surgical pleurodesis for malignant pleural effusion.
VATS-Surgical pleurodesis
VATS drainage and surgical abrasion.
Tube drainage
Patients in whom we use tube drainage for malignant pleural effusion.
Tube Drainage
Tube drainage for malignant pleural effusion
Interventions
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VATS-Surgical pleurodesis
VATS drainage and surgical abrasion.
Tube Drainage
Tube drainage for malignant pleural effusion
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2. Pleural symphysis with no potentiality for re-expansion
3. Patients managed surgically through open thoracotomy.
4. Pleural effusion due to causes other than malignancy
5. Loculated malignant effusion judged by chest ultrasound
6. Trapped lung due to malignant pleural effusion assessed by multislice CT chest.,
7. .Refusal to share the research project and not to sign the consent.
5 Years
90 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Kareem Ahmed Hosny
Principle investigator
Locations
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Assiut university heart hospital
Asyut, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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AssiutMedicCTS
Identifier Type: -
Identifier Source: org_study_id
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