Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars
NCT ID: NCT06962878
Last Updated: 2025-08-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
20 participants
INTERVENTIONAL
2025-08-05
2026-03-05
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
* The participants will be blinded to the technique that will be used during the surgical procedure.
* The operator will not be blinded for both techniques during the surgical procedure as the two techniques are different.
* The outcome assessor cannot be blinded.
Study Groups
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Xenograft
Xenograft
The jumping gap and surrounding space will be augmented and packed with Xenograft
Allograft
Allograft
The jumping gap and surrounding space will be augmented and packed with Allograft
Interventions
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Xenograft
The jumping gap and surrounding space will be augmented and packed with Xenograft
Allograft
The jumping gap and surrounding space will be augmented and packed with Allograft
Eligibility Criteria
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Inclusion Criteria
* Both sexes with age range from 25 years to 40 years
* Good oral hygiene
* Adequate alveolar bone dimensions for implant replacement
* Adequate bone volume after extraction to achieve primary stability of the immediate implant
* Co-operative patient
Exclusion Criteria
* Heavy smokers with smokers more than 10 cigarettes per day
* Pregnancy
* Patients with any signs of active infection or pus formation
* Patients undergoing chemotherapy or radiotherapy, immunocompromised patients
25 Years
40 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Ahmed Mohamed Mohamed Tawfik
Dentist
Principal Investigators
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Mohamed Atef, PhD
Role: STUDY_DIRECTOR
Cairo University
Locations
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Faculty of Dentistry, Cairo University
Cairo, , Egypt
Countries
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Central Contacts
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Facility Contacts
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References
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Botticelli D, Berglundh T, Buser D, Lindhe J. The jumping distance revisited: An experimental study in the dog. Clin Oral Implants Res. 2003 Feb;14(1):35-42. doi: 10.1034/j.1600-0501.2003.140105.x.
Bhola M, Neely AL, Kolhatkar S. Immediate implant placement: clinical decisions, advantages, and disadvantages. J Prosthodont. 2008 Oct;17(7):576-81. doi: 10.1111/j.1532-849X.2008.00359.x. Epub 2008 Aug 26.
Lang NP, Pun L, Lau KY, Li KY, Wong MC. A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res. 2012 Feb;23 Suppl 5:39-66. doi: 10.1111/j.1600-0501.2011.02372.x.
Dimitriou R, Mataliotakis GI, Angoules AG, Kanakaris NK, Giannoudis PV. Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review. Injury. 2011 Sep;42 Suppl 2:S3-15. doi: 10.1016/j.injury.2011.06.015. Epub 2011 Jun 25.
Khoury F, Hanser T. Mandibular bone block harvesting from the retromolar region: a 10-year prospective clinical study. Int J Oral Maxillofac Implants. 2015 May-Jun;30(3):688-97. doi: 10.11607/jomi.4117.
Schropp L, Isidor F. Timing of implant placement relative to tooth extraction. J Oral Rehabil. 2008 Jan;35 Suppl 1:33-43. doi: 10.1111/j.1365-2842.2007.01827.x.
Alexopoulou M, Lambert F, Knafo B, Popelut A, Vandenberghe B, Finelle G. Immediate implant in the posterior region combined with alveolar ridge preservation and sealing socket abutment: A retrospective 3D radiographic analysis. Clin Implant Dent Relat Res. 2021 Feb;23(1):61-72. doi: 10.1111/cid.12974. Epub 2021 Jan 13.
Howe MS, Keys W, Richards D. Long-term (10-year) dental implant survival: A systematic review and sensitivity meta-analysis. J Dent. 2019 May;84:9-21. doi: 10.1016/j.jdent.2019.03.008. Epub 2019 Mar 20.
Adell R, Lekholm U, Rockler B, Branemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg. 1981 Dec;10(6):387-416. doi: 10.1016/s0300-9785(81)80077-4.
Kononen E, Gursoy M, Gursoy UK. Periodontitis: A Multifaceted Disease of Tooth-Supporting Tissues. J Clin Med. 2019 Jul 31;8(8):1135. doi: 10.3390/jcm8081135.
Related Links
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Other Identifiers
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Grafting in immediate implants
Identifier Type: -
Identifier Source: org_study_id
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