Post-Traumatic Growth Following Eye Movement Desensitization and Reprocessing Therapy Versus SSRIs in Patients With Post-Traumatic Stress Disorder

NCT ID: NCT06957210

Last Updated: 2025-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-06

Study Completion Date

2025-12-31

Brief Summary

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This randomized controlled trial investigates the comparative effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy and selective serotonin reuptake inhibitors (SSRIs) in fostering post-traumatic growth among patients diagnosed with post-traumatic stress disorder (PTSD). Participants will be randomized to receive either EMDR therapy or standard SSRI pharmacotherapy. The primary objective is to evaluate the extent of psychological growth and recovery achieved through each intervention, aiming to guide future therapeutic strategies for PTSD.

Detailed Description

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Conditions

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PTSD - Post Traumatic Stress Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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EMDR

EMDR therapy

Group Type EXPERIMENTAL

EMDR

Intervention Type BEHAVIORAL

Participants will receive structured EMDR therapy sessions conducted by trained therapists following standard EMDR protocols. Sessions will occur weekly over a 6 week period.

SSRIs

Acting as control group

Group Type ACTIVE_COMPARATOR

SSRIs

Intervention Type DRUG

Participants will receive pharmacotherapy with an SSRI prescribed according to standard clinical guidelines for PTSD, monitored by a psychiatrist over a 6-week period.

Interventions

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EMDR

Participants will receive structured EMDR therapy sessions conducted by trained therapists following standard EMDR protocols. Sessions will occur weekly over a 6 week period.

Intervention Type BEHAVIORAL

SSRIs

Participants will receive pharmacotherapy with an SSRI prescribed according to standard clinical guidelines for PTSD, monitored by a psychiatrist over a 6-week period.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Clinical diagnosis of Post-Traumatic Stress Disorder (PTSD) based on DSM-5 criteria

Willingness to participate and provide informed consent

Ability to comply with study procedures

Exclusion Criteria

Current diagnosis of psychotic disorder, bipolar disorder, or severe major depressive episode with psychotic features

Active substance use disorder within the past 6 months

Severe cognitive impairment or inability to complete study assessments
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CMH Nowshera

UNKNOWN

Sponsor Role collaborator

Asad Ullah Jan

OTHER_GOV

Sponsor Role lead

Responsible Party

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Asad Ullah Jan

Head Department of Psychiatry

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Combined Military Hospital

Nowshera, KPK, Pakistan

Site Status

Department of Psychiatry, Combined Military Hospital Nowshera

Nowshera, KPK, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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CMHNSR-REF-15

Identifier Type: -

Identifier Source: org_study_id

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