Neurofeedback for Post-Traumatic Stress Disorder

NCT ID: NCT05123690

Last Updated: 2023-04-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2025-12-31

Brief Summary

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A two-arm randomized pilot of standard neurofeedback and a waiting list for patients with treatment resistent PTSD.

Detailed Description

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This study will be a randomized-controlled pilot and in a later study virtual reality based neurofeedback will be tested. In this study 30 subjects will be randomised into one of two arms of the study. Treatment as usual (TAU) entails both psychotherapy, medication and other interventions.

1. TAU + Neurofeedback using a PC-screen (experimental group)
2. TAU as a waiting list (control group) - the participants in the control group will be offered to choose one of the two experimental treatments at the end of the trial.

The 30 participants will be randomized to one arm of the study (15 participants per group). The subjects will be recruited from Psychiatric Outpatient Care at Sahlgrenska University Hospital, Crisis and Trauma Center Gothenburg and Psychiatric Care Center in Tranås, Jönköping.

Participants in the experimental group will have 24 sessions in total, (twice a week. 12 week period) with a trained neurofeedback specialist or trained neurofeedback physician. Before session 1 and after session 24, a clinician will fill in the clinical scales and questionnaires.

Conditions

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Post-traumatic Stress Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Allocation is to one of two arms
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Statistical analysis will be done seperately

Study Groups

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Neurofeedback

24 sessions of ca 45 minutes neurofeedback using alpha-theta protocol.

Group Type EXPERIMENTAL

Neurofeedback

Intervention Type DEVICE

A device that assists in training patients in relaxing.

Waiting list

Those assigned to waiting list will be able to pick one of the two interventions at the end of the study.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Neurofeedback

A device that assists in training patients in relaxing.

Intervention Type DEVICE

Other Intervention Names

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EEG assisted neurofeedback Biofeedback

Eligibility Criteria

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Inclusion Criteria

* CAPS Cutoff \>44
* Stable psychopharmacological treatment (stable dose, no planned changes during the course of the trial)
* AUDIT cut off \<16
* DUDIT cut off \<8
* Already undergone at least one treatment with psychotherapy and/or pharmacological treatment for a minimum of 6 months.
* 18 years or older

Exclusion Criteria

* Diagnosis of traumatic brain injury (TBI) affecting capability to give informed consent
* Ongoing traumatic exposure (such as domestic violence)
* Balance problems
* Active suicide risk or life-threatening self-harm
* A diagnosis of schizophrenia or psychotic disorder
* Ongoing compulsory care
* If the patient changes dose or medication strategy during the trial.
* If the neurofeedback treatment is identified as a primary reason for worsening of participant's well being.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Steinn Steingrimsson

OTHER

Sponsor Role lead

Responsible Party

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Steinn Steingrimsson

Principal investigator & clinical associate professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Steinn Steingrimsson, PhD

Role: PRINCIPAL_INVESTIGATOR

Sahlgrenska University Hospital

Locations

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Sahlgrenska University Hospital

Gothenburg, Västra Götaland County, Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Steinn Steingrimsson, PhD

Role: CONTACT

0046313421000

Facility Contacts

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Steinn Steingrimsson, MD, PhD

Role: primary

Other Identifiers

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SUNF001

Identifier Type: -

Identifier Source: org_study_id

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