Efficacy of Eye Movement Desensitization and Reprocessing (EMDR) Therapy Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in the Treatment of Post-Traumatic Stress Disorder

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-06

Study Completion Date

2025-12-31

Brief Summary

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This randomized controlled trial aims to compare the efficacy of Eye Movement Desensitization and Reprocessing (EMDR) therapy versus Selective Serotonin Reuptake Inhibitors (SSRIs) in the treatment of Post-Traumatic Stress Disorder (PTSD). Adult patients diagnosed with PTSD will be randomly assigned to receive either EMDR therapy or SSRIs for a period of six weeks. The primary outcome is the rate of remission as measured by validated PTSD symptom severity scales at Week 6. Secondary outcomes include changes in functional impairment and patient-reported quality of life. The study seeks to determine whether EMDR therapy is a non-pharmacological alternative to SSRIs for achieving symptom remission in PTSD.

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Detailed Description

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Conditions

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PTSD PTSD - Post Traumatic Stress Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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EMDR Therapy

Participants will receive Eye Movement Desensitization and Reprocessing (EMDR) therapy over six weeks.

Group Type EXPERIMENTAL

Eye Movement Desensitization and Reprocessing Therapy

Intervention Type BEHAVIORAL

Patients in this arm will receive weekly EMDR sessions for 6 weeks

Selective Serotonin Reuptake Inhibitors (SSRIs)Treatment

Participants will receive selective serotonin reuptake inhibitors (SSRIs) such as Sertraline over six weeks.

Group Type ACTIVE_COMPARATOR

Selective serotonin reuptake inhibitors

Intervention Type DRUG

The patients will receive an SSRI medication daily for 6 weeks. The dose will be titrated by the clinician.

Interventions

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Eye Movement Desensitization and Reprocessing Therapy

Patients in this arm will receive weekly EMDR sessions for 6 weeks

Intervention Type BEHAVIORAL

Selective serotonin reuptake inhibitors

The patients will receive an SSRI medication daily for 6 weeks. The dose will be titrated by the clinician.

Intervention Type DRUG

Other Intervention Names

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EMDR Therapy

Eligibility Criteria

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Inclusion Criteria

Age 18-60 years

Clinical diagnosis of Post-Traumatic Stress Disorder (PTSD)

Duration of illness ≥ 6 months

Able to provide informed consent

Exclusion Criteria

Current substance abuse or dependence

History of psychotic disorder or bipolar disorder

Active suicidal ideation

Concurrent psychotherapy or psychiatric medication (except study-assigned SSRI)

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No