Early Oral Fluid Intake in Children After Day Surgery

NCT ID: NCT06937684

Last Updated: 2025-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-01

Study Completion Date

2025-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study investigates the safety and tolerability of early oral clear fluid intake in children aged 1-8 years undergoing elective outpatient non-gastrointestinal surgeries. Patients will be randomized to receive clear fluids either at 1 hour or 2 hours after general anesthesia. The goal is to determine whether earlier fluid intake increases the risk of postoperative vomiting (POV), or whether it can be safely tolerated in pediatric patients."

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This prospective, randomized controlled clinical trial aims to evaluate the safety and tolerability of early oral clear fluid intake in children aged 1 to 8 years undergoing elective, outpatient, non-gastrointestinal surgery under general anesthesia. Recent guidelines recommend reducing preoperative and postoperative fasting durations in children to enhance recovery and well-being. Early postoperative hydration has been associated with reduced opioid requirements, faster return to normal diet and ambulation, and shorter hospital stay, without increasing the risk of postoperative nausea and vomiting (PONV).

In this study, participants will be randomly assigned to one of two groups. Group E (early group) will receive up to 10 ml/kg of clear fluids (e.g., water, clear juice) one hour after the end of anesthesia, while Group T (traditional group) will receive the same amount two hours after anesthesia. Patients will be evaluated for readiness to drink based on recovery of consciousness, protective airway reflexes, and absence of nausea or vomiting. Fluid will be administered slowly and under strict supervision by experienced staff, with emergency equipment readily available.

The incidence of vomiting will be assessed using a modified 4-point scale. Additional outcome measures include tolerability of oral fluids, time to readiness for discharge, and incidence of delayed postoperative vomiting on postoperative days 1 and 3, assessed via phone interviews with caregivers. This study seeks to provide evidence-based guidance on the optimal timing and volume of clear fluid intake in pediatric patients following ambulatory minor surgical procedures, contributing to more flexible and patient-centered perioperative fasting protocols.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pediatric Anesthesia Postoperative Nausea and Vomiting (PONV) Ambulatory Surgical Procedures

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a two-arm, parallel-group, randomized controlled trial. Participants will be randomly assigned to one of two groups to receive a maximum of 10 ml/kg of clear fluids either 1 hour (early group) or 2 hours (traditional group) after general anesthesia. Each participant will be assigned to only one group and will receive the intervention once.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors
Only the outcomes assessor (the nurse responsible for evaluating postoperative vomiting) is blinded to the group assignments. No other study personnel, caregivers, or participants are masked in this trial.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Early Oral Intake Group (Group E)

Patients in this group will receive a maximum of 10 ml/kg of clear fluids (e.g., water or clear fruit juice) starting at 1 hour after the completion of general anesthesia.

Group Type EXPERIMENTAL

Early Oral Fluid Intake

Intervention Type BEHAVIORAL

Participants receive clear fluids up to 10 ml/kg at 1 hour after anesthesia.

Traditional Oral Intake Group (Group T)

Patients in this group will receive a maximum of 10 ml/kg of clear fluids (e.g., water or clear fruit juice) starting at 2 hours after the completion of general anesthesia.

Group Type ACTIVE_COMPARATOR

Traditional Oral Fluid Intake

Intervention Type BEHAVIORAL

Participants receive clear fluids up to 10 ml/kg at 2 hours after anesthesia.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Early Oral Fluid Intake

Participants receive clear fluids up to 10 ml/kg at 1 hour after anesthesia.

Intervention Type BEHAVIORAL

Traditional Oral Fluid Intake

Participants receive clear fluids up to 10 ml/kg at 2 hours after anesthesia.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Children aged between 1 and 8 years
* ASA Physical Status I or II
* Undergoing elective, outpatient, non-gastrointestinal surgery under general anesthesia
* Expected to be discharged on the same day
* Parent/guardian provides informed consent

Exclusion Criteria

* Emergency surgeries
* History of gastrointestinal disorders
* History of aspiration or recurrent vomiting
* Children with neurodevelopmental delay
* Intraoperative complications requiring ICU admission
* Refusal of oral intake postoperatively
Minimum Eligible Age

1 Year

Maximum Eligible Age

8 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ankara City Hospital Bilkent

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Feyza Sever, Assoc Prof

Role: PRINCIPAL_INVESTIGATOR

Ankara City Hospital Bilkent

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Ankara City Hospital Bilkent

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Turkey (Türkiye)

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Feyza Sever, Assoc Prof

Role: CONTACT

+9031255260000

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Feyza Sever, Assoc Prof

Role: primary

+903125526000

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

E2-24-6970

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Oral Fluid Intake After Extubation
NCT05819645 COMPLETED NA