Effect of Drinking Carbohydrate-containing Fluids on Gastric Residual Volume in Elderly Patients

NCT ID: NCT04514380

Last Updated: 2021-03-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

64 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-16

Study Completion Date

2021-03-19

Brief Summary

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In the past, some guidelines advised no oral intake for at least 8 hours before any surgery. However, research has shown risks associated with excessive fasting, such as postoperative insulin resistance, and advantages in shorter fasting protocols, such as reduced postoperative nausea and vomiting.

The perioperative fasting guidelines of the European Society of Anaesthesiology focus on preoperative carbohydrates. They hold that it is safe for patients to drink carbohydrate-rich fluids up to 2 hours before elective surgery and that drinking carbohydrate-rich fluids improves subjective well-being, reduces thirst and hunger, and reduces postoperative insulin resistance at an evidence level of 1++. Nevertheless, data on drinking carbohydrate fluids before surgery in elderly patients are limited.

In our institution, there are two clinical pathways for total knee arthroplasty according to the surgeons. One difference is whether carbohydrate fluids drink or not before surgery. The purpose of this study, therefore, is to assess gastric volume in fasted elderly patients using ultrasound after they drank carbohydrate fluids 2 hours before surgery and to compare with matched patients using age, body mass index, and comorbidity, who did not drink carbohydrate fluids before surgery.

Detailed Description

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Conditions

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Fasting

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group C

Patients drank carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon A.

Carbohydrate fluid

Intervention Type OTHER

400 mL carbohydrate fluid

Group N

Patients did not drink carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon B.

Non-carbohydrate fluid

Intervention Type OTHER

0 mL carbohydrate fluid

Interventions

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Carbohydrate fluid

400 mL carbohydrate fluid

Intervention Type OTHER

Non-carbohydrate fluid

0 mL carbohydrate fluid

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing total knee arthroplasty
* Age: 65\~85 yeas
* ASA 1\~3

Exclusion Criteria

* Age \< 65 years
* ASA \>= 4
* Diabetes mellitus
* Chronic kidney disease
Minimum Eligible Age

65 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Bundang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hyo-Seok Na

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hyo-Seok Na, MD., PhD.

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Bundang Hospital

Locations

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Seoul National Univ. Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea

Site Status

Countries

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South Korea

References

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Shin HJ, Koo BW, Lim D, Na HS. Ultrasound assessment of gastric volume in older adults after drinking carbohydrate-containing fluids: a prospective, nonrandomized, and noninferiority comparative study. Can J Anaesth. 2022 Sep;69(9):1160-1166. doi: 10.1007/s12630-022-02262-9. Epub 2022 Apr 21.

Reference Type DERIVED
PMID: 35449247 (View on PubMed)

Other Identifiers

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B-2008/633-301

Identifier Type: -

Identifier Source: org_study_id

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