Remote Alert Pathway To Optimize CaRe of Cardiac Implantable Electrical Devices

NCT ID: NCT06937658

Last Updated: 2026-01-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-01

Study Completion Date

2026-06-30

Brief Summary

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The Remote Alert Pathway to Optimize Care of Cardiac Implantable Electrical Devices (RAPTOR-CIED) Study is a pragmatic, multi-center, randomized trial with 1:1 patient-level randomization comparing the safety and effectiveness of alert-driven care versus guideline-based care for patients with wireless cardiac implantable electrical devices (CIEDs).

The study will be conducted in 2 phases: a Feasibility Phase and a Main Phase. This registration outlines the goals and design features of the Feasibility Phase of the study.

Detailed Description

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Conditions

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Pacemaker DDD Implantable Defibrillator User

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Guideline-based Care

Remote monitoring programming scheduled for alert transmissions, patient-initiated transmissions, and routine transmissions (scheduled to occur every 90 days from the date of enrollment in the study); in-office interrogations on at least an annual basis

Group Type ACTIVE_COMPARATOR

Guideline-based care

Intervention Type DEVICE

Guideline-based care is the current typical standard for longitudinal management of patients with wireless pacemakers and implantable defibrillators

Alert-based Care

Remote monitoring programming scheduled for alert transmissions and patient-initiated transmissions only

Group Type ACTIVE_COMPARATOR

Alert-based care

Intervention Type DEVICE

Alert-based care is an alternative strategy for longitudinal management of patients with wireless pacemakers and implantable defibrillators

Interventions

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Alert-based care

Alert-based care is an alternative strategy for longitudinal management of patients with wireless pacemakers and implantable defibrillators

Intervention Type DEVICE

Guideline-based care

Guideline-based care is the current typical standard for longitudinal management of patients with wireless pacemakers and implantable defibrillators

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Adult aged \> 18 years
2. Clinically stable by investigator assessment
3. Has a newly implanted or existing wireless CIED: single, dual-chamber, biventricular, subcutaneous/extravascular, and leadless systems are all eligible, including pacemakers or implantable cardioverter-defibrillators (ICDs)
4. CIED is from one of the 4 major CIED manufacturers in the US market (99% of implants in the US): Medtronic, Boston Scientific, Abbott, Biotronik
5. Currently enrolled in remote monitoring as part of standard of care
6. Primary clinical electrophysiology follow-up at the enrolling center
7. Understands spoken and written English, Spanish, or Portuguese
8. Has sufficient cognitive function to answer standardized questions about study rationale and procedures.

Exclusion Criteria

1. Presence of insertable cardiac monitor, either in isolation or in combination with any other CIED
2. Listed for cardiac transplantation prior to enrollment (N.B. if a patient becomes listed for transplantation during the study, they may continue study participation)
3. Participation in another study related to novel CIED technology or remote monitoring.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beth Israel Deaconess Medical Center

OTHER

Sponsor Role lead

Patient-Centered Outcomes Research Institute

OTHER

Sponsor Role collaborator

Responsible Party

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Daniel B. Kramer

Associate Professor of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Linda Valsdottir, MS

Role: CONTACT

6176678800

Facility Contacts

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Daniel B Kramer, MD

Role: primary

617-667-8800

Linda Valsdottir, MS

Role: backup

617-632-7652

Other Identifiers

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PLACER-2023C3-34968

Identifier Type: -

Identifier Source: org_study_id

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