Reduction of Inappropriate Shocks of Implantable Cardioverter Defibrillators (ICDs) With Enhanced SVT Discriminators

NCT ID: NCT01963286

Last Updated: 2019-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

735 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-08-31

Study Completion Date

2016-10-31

Brief Summary

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The purpose of this clinical investigation is the continued assessment of the decision accuracy of St. Jude Medical (SJM) ICD with enhanced SVT discriminators in the treatment of subjects with primary and secondary prevention of sudden cardiac death.

Detailed Description

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With Ellipse™ and Fortify Assura™ ICD family, St. Jude Medical introduced enhanced device algorithms that may be helpful to further improve SVT discrimination success: SecureSense™, Far field morphology, Chamber Onset. These algorithms in combination with a tailored device setting (primary or secondary prevention) will be prospectively investigated within this trial.

Conditions

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Tachycardia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Enhanced SVT discriminators

Patients with activated enhanced SVT discriminators (in accordance with predefined mandatory study settings)

Group Type OTHER

ICD with enhanced SVT discriminators

Intervention Type DEVICE

ICD will be programmed to uniform device settings with enhanced SVT discrimintators enabled.

Interventions

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ICD with enhanced SVT discriminators

ICD will be programmed to uniform device settings with enhanced SVT discrimintators enabled.

Intervention Type DEVICE

Other Intervention Names

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Ellipse (St. Jude Medical) Fortify Assura (St. Jude Medical) Unify Assura (St. Jude Medical)

Eligibility Criteria

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Inclusion Criteria

* Ischemic or nonischemic cardiomyopathy
* Primary prevention or secondary prevention of Sudden cardiac death (SCD)
* Indication for ICD/CRT-D new implantation per current guidelines (1, 2, 3-chamber)
* The patient is ≥ 18 years of age
* The patient is able to understand the patient information and is capable to provide informed consent.
* The patient has provided written informed consent prior to any investigational related procedure

Exclusion Criteria

* Previously implanted ICD/CRT-D
* Hypertrophic (with or without obstructive) cardiomyopathy
* Ion channel disorders (Long/Short-QT, Brugada syndrome etc…)
* New York Heart Association (NYHA) Class IV
* Recent cardiac decompensation (within previous 3 months)
* The patient is unable to comply with the follow up schedule.
* The patient is participating in another investigational device or drug investigation.
* The patient is pregnant or is planning to become pregnant during the duration of the investigation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Devices

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Johann C Geller, Prof. Dr.

Role: STUDY_CHAIR

Zentralklinik Bad Berka

Locations

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Praxis Dr. med. Bernhardt

Annaberg-Buchholz, , Germany

Site Status

Zentralklinik Bad Berka GmbH

Bad Berka, , Germany

Site Status

Hufeland Klinikum GmbH

Bad Langensalza, , Germany

Site Status

Caritas Krankenhaus

Bad Mergentheim, , Germany

Site Status

North Estonia Medical Centre

Tallinn, , Estonia

Site Status

Tartu University Hospital

Tartu, , Estonia

Site Status

Medizinisches Versorgungszentrum am Küchwald GmbH

Chemnitz, , Germany

Site Status

Praxis Dr. med. Stellmach

Chemnitz, , Germany

Site Status

Klinikum Coburg GmbH

Coburg, , Germany

Site Status

Evangelisches Krankenhaus Kalk gGmbH

Cologne, , Germany

Site Status

Klinikum Esslingen

Esslingen am Neckar, , Germany

Site Status

Universitäts-Herzzentrum Freiburg - Bad Krozingen

Freiburg im Breisgau, , Germany

Site Status

Medizinische Hochschule Hannover

Hanover, , Germany

Site Status

Oberhavel Kliniken GmbH Klinik Hennigsdorf

Hennigsdorf, , Germany

Site Status

Evangelisches Krankenhaus Holzminden gGmbH

Holzminden, , Germany

Site Status

Praxis Frau Dr. med. Gärtner

Leisnig, , Germany

Site Status

Klinikum der Stadt Ludwigshafen am Rhein gGmbH

Ludwigshafen, , Germany

Site Status

Klinikum Memmingen

Memmingen, , Germany

Site Status

Universitätsklinikum Münster

Münster, , Germany

Site Status

Klinikum Oldenburg gGmbH

Oldenburg, , Germany

Site Status

Christliches Krankenhaus Quakenbrück gGmbH

Quakenbrück, , Germany

Site Status

Gem.-Praxis Dres. med. Ebert / Stenzel

Riesa, , Germany

Site Status

Hegau-Bodensee-Klinikum mbH

Singen, , Germany

Site Status

Countries

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Estonia Germany

Other Identifiers

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CR-12-092-GE-HV

Identifier Type: -

Identifier Source: org_study_id

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