Benefits of Early Proprioceptive Re-education Without Visual Information After Total Knee Arthroplasty

NCT ID: NCT06936267

Last Updated: 2025-04-20

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 66 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-06-01
• Study Completion Date: 2026-06-22

Brief Summary

Osteoarthritis is a common and disabling joint disease, affecting 4.7% of men and 6.6% of women in France. It causes pain and impaired joint mobility, as well as a reduction in proprioception due to damage to intra-articular mechanoreceptors. In the long term, gonarthrosis can lead to limitations in activities of daily living and increase the risk of falls and institutionalisation.

Total knee arthroplasty is an effective treatment for reducing pain and improving functional capacity. However, 50% of patients operated on are not satisfied with the results obtained at 6 months, and between 37% and 55% experience no significant improvement in their functional mobility. It is therefore important to better define the modalities of rehabilitation interventions in order to improve their efficiency and the functional benefits for the patient.

Proprioception, the visual system and the vestibular system are the three major systems involved in posture and balance. Rehabilitation interventions aimed at improving balance involve these three inputs and their interaction. Studies have shown that proprioceptive rehabilitation can significantly improve balance and gait in patients who have undergone total knee arthroplasty. However, visual feedback may hinder the development of balance skills by limiting the use of other sensorimotor systems.

Detailed Description

The aim of this research project is to determine the benefits of visual deprivation and the methods of early proprioceptive exercises, right from the start of rehabilitation, on postural control in patients following total knee arthroplasty. Proprioceptive re-education with the eyes closed will be used from the very first rehabilitation sessions, evaluating its effect on proprioception. Currently, only one study has looked at the influence of the visual system in proprioceptive rehabilitation after total knee arthroplasty, seeking to assess the superiority of exercises with visual feedback compared with exercises without such feedback. The investigator presents an opposite and innovative questioning by proposing to evaluate on a larger scale the influence of visual deprivation rather than visual feedback.

Conditions

Unilateral Primary Osteoarthritis, Left Knee

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: SINGLE

Study Groups

proprioceptive exercise with eyes open

• 30 minutes of techniques to increase joint amplitude
• 15 to 30 minutes of muscular strengthening of the hamstrings against resistance (elastic or pulley), of the quadriceps without resistance and then against a light weight (1 to 2 kg).
• 15 to 30 minutes of proprioceptive exercises, eyes open.
• 10 to 15 minutes of functional exercises: walking, overcoming obstacles, going up and down stairs
• 20 minutes of pressure therapy

Group Type: ACTIVE_COMPARATOR

rehabilitation : eyes open

Intervention Type: OTHER

proprioceptive exercise with eyes open

proprioceptive exercise with eyes closed

• 30 minutes of techniques to increase joint amplitude
• 15 to 30 minutes of muscular strengthening of the hamstrings against resistance (elastic or pulley), of the quadriceps without resistance and then against a light weight (1 to 2 kg).
• 15 to 30 minutes of proprioceptive exercises, eyes closed
• 10 to 15 minutes of functional exercises: walking, overcoming obstacles, going up and down stairs
• 20 minutes of pressure therapy

Group Type: EXPERIMENTAL

rehabilitation : eyes closed

Intervention Type: OTHER

proprioceptive exercise with eyes closed

Interventions

rehabilitation : eyes closed

proprioceptive exercise with eyes closed

Intervention Type: OTHER

rehabilitation : eyes open

proprioceptive exercise with eyes open

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patient aged between 60 and 85 having undergone primary total knee arthroplasty for gonarthrosis
• Patient admitted to a Continuing Care and Rehabilitation (CCR) department and having received a maximum of 1 functional re-education session
• Patient able to remain in bipodal support with eyes closed for 30 seconds on inclusion
• Weight below the limit accepted by the posturography platform (100 kg)
• Patient having read and understood the information letter and having signed the consent form
• Affiliation with the social security system

Exclusion Criteria

• Blindness
• Diabetes with peripheral neuropathy
• Central or peripheral nerve pathology (cerebellar syndrome, stroke sequelae, etc.)
• Previously known ataxia
• Alcoholism not withdrawn
• Pre-existing gait disorders making assessment impossible
• Disorders of the vestibular system
• Inflammatory rheumatism
• Length of stay in surgery > 7 days
• Person deprived of liberty by administrative or judicial decision or person placed under court protection / sub-guardianship or guardianship

• Minimum Eligible Age: 60 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Rouen

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Timothée GILLOT

Role: PRINCIPAL_INVESTIGATOR

UH ROUEN

Locations

CRMPR - les herbiers

Bois-Guillaume, , France

Chu Rouen

Rouen, , France

Countries

France

Central Contacts

Timothée GILLOT, PhD, MKDE

Role: CONTACT

timothee.gillot@chu-rouen.fr

02 32 88 06 71

déborah lebedieff

Role: CONTACT

deborah.lebedieff@chu-rouen.fr

0232888265

Other Identifiers

2019/072/HP

Identifier Type: -

Identifier Source: org_study_id