Ultrasound Assessment of Atherosclerotic Plaque Burden and Cardiovascular Risk: A 10-Year Prospective Study

NCT ID: NCT06933745

Last Updated: 2025-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

21029 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-04-01

Study Completion Date

2025-03-01

Brief Summary

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The P-SONAR study is a large, observational, prospective cohort study. The overall aim of the study is to investigate whether plaque burden estimation by 2D ultrasound of the carotid and femoral arteries may enhance cardiovascular risk prediction beyond NORRISK-2

Detailed Description

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Design: The P-SONAR Study is a prospective cohort study of all men and women aged 45-74 years attending a health check at one of 10 ultrasound clinics in Norway.

Time schedule: Study inclusion and baseline examinations took place in the period April 2022- March 20025.

Current status: Ultrasound follow-up examinations take place from January 2025 - December 2029.

Conditions

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Cardiovascular Diseases Fatty Liver Atherosclerosis of Femoral Artery Carotid Artery Plaque Stroke Ischemic Cardiovascular Disease Atheroscleroses

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Participants undergoing ultrasound and screening for conventional CV risk factors.

A sub-cohort consists of 5 500 participants who undergo both carotid and femoral ultrasound and fatty liver status assessment by ultrasound, in addition to assessement of traditional CV risk factors including history of smoking, total-cholesterol, LDL-cholesterol, HDL-cholesterol, Lp(a), blood glucose, systolic and diastolic blood pressure and waist circumference measurements.

No interventions assigned to this group

Participants undergoing ultrasound examination

Total cohort consists of 22 000 participants who undergo both carotid and femoral ultrasound and fatty liver status assessment by ultrasound

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

* If they do not consent to participate
Minimum Eligible Age

45 Years

Maximum Eligible Age

74 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Oslo

OTHER

Sponsor Role collaborator

University Hospital, Akershus

OTHER

Sponsor Role lead

Responsible Party

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Jonn Terje Geitung

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jonn-Terje Geitung, MD, PhD, MHA

Role: PRINCIPAL_INVESTIGATOR

University of Oslo

Serena N.H. Tonstad, MD, PhD

Role: STUDY_DIRECTOR

Oslo University Hospital

Locations

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Austad Diagnostikk

Oslo, East, Norway

Site Status

Countries

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Norway

Other Identifiers

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Ahus, BDA

Identifier Type: -

Identifier Source: org_study_id

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