Real-Time (TRUS) Guidance in Endoscopic Treatment of BPH
NCT ID: NCT06922968
Last Updated: 2025-04-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
114 participants
INTERVENTIONAL
2025-04-01
2026-10-01
Brief Summary
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Detailed Description
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TRUS, widely utilized for prostate biopsy and volume assessment, has recently gained attention for its intraoperative applications. Studies show that real-time TRUS provides accurate imaging of prostate anatomy and resection planes, helping surgeons better differentiate adenomatous tissue from surrounding structures. This enhances surgical precision, reduces intraoperative bleeding, and minimizes residual tissue, leading to better outcomes in procedures like TURP and enucleation.
Current TURP and enucleation approaches depend heavily on endoscopic visual guidance, which, despite significant advancements, can lead to residual tissue, excessive bleeding, and prolonged recovery. While enucleation techniques have addressed some of these challenges, they remain less accessible due to high costs and steep learning curves, making them unsuitable for all healthcare settings.
Integrating TRUS into TURP or enucleation offers the potential to address these limitations by enhancing tissue differentiation and guiding precise resection. This study aims to evaluate the efficacy of TRUS in reducing complications, achieving complete tissue removal, and improving patient recovery outcomes, potentially paving the way for its routine adoption in BPH surgery.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Control group
Control cases under went TURP and enucleation
Standard TURP and enucleation
No TRUS guidance during the procedure (TURP and enucleation)
TRUS Guided group
TRUS guided group during TURP and enucleation
TRUS-Guided TURP and enucleation
realtime TRUS guidance during the procedure (TURP and enucleation)
Interventions
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TRUS-Guided TURP and enucleation
realtime TRUS guidance during the procedure (TURP and enucleation)
Standard TURP and enucleation
No TRUS guidance during the procedure (TURP and enucleation)
Eligibility Criteria
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Inclusion Criteria
* Diagnosed with benign prostatic hyperplasia (BPH) and scheduled for TURP or prostatic adenoma enucleation.
* The patients have clear indication for endoscopic surgery (according to the guidelines).
* Clinically fit patients for surgery.
* Signed an informed consent.
Exclusion Criteria
* Previous urethral or prostate surgery
* Neurogenic bladder
* Urethral stricture
50 Years
80 Years
MALE
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Mohamed ElSharkawy
Principal Investigator
Principal Investigators
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Ahmed Mohamed Abdel-Moniem Hassanein, professor of Urology
Role: STUDY_DIRECTOR
Assiut University
Locations
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Assiut university
Asyut, , Egypt
Countries
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Central Contacts
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Mohamed mostafa Elsharkawy, assistant lecturer of Urology
Role: CONTACT
Other Identifiers
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TRUS with TURP and enucleation
Identifier Type: -
Identifier Source: org_study_id
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