Stress Evaluation and Management Using High Fidelity Simulation in Medical Education

NCT ID: NCT06916949

Last Updated: 2025-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-30

Study Completion Date

2025-05-31

Brief Summary

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The goal of this interventional study is to collect clinical and neurophysiological information to determine whether high-fidelity simulation can serve as a stress-inducing stimulus in a population of healthy residents (Emergency medicine, Anesthesia and Intensive care medicine, Paediatrics), both male and female, aged between 25 and 40 years. The main questions it aims to answer are:

1. Define in which phase of the simulation the highest level of stress is observed.
2. Determine the level of stress reached after performing a second high-fidelity simulation after a period of time.
3. Identify whether specific brain areas are activated during high-fidelity simulation.

Participants will form teams, consisting of three medical trainees from the same specialty training program, that will undergo two high-fidelity simulations based on a clinical scenario relevant to their residency.

* During the simulation, automatic pupillometry will be performed on all team members at the four time points.
* Additionally, a two-lead ECG will be recorded for all team members at baseline and end of the debriefing
* One team member will undergo EEG monitoring throughout the entire simulation. The EEG recordings will be sampled at baseline, during the simulation and end of the debriefing.

Detailed Description

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Conditions

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Stress Pupillometry High Fidelity Simulation Training Resident Education Heart Rate Variability, Biomarker of Stress Simulation Training

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Simulation team

All participants will be divided in teams, each one consisting of three medical trainees from the same specialty training program, and all of them will undergo two high-fidelity simulations based on a clinical scenario relevant to their specialization.

Group Type EXPERIMENTAL

Electrocardiogram

Intervention Type DIAGNOSTIC_TEST

two leads ECG

Pupillometry

Intervention Type DIAGNOSTIC_TEST

During the simulation, automatic pupillometry will be performed on all team members at the following time points: Baseline (T0) During the simulation (T1) End of the simulation (T2) End of the debriefing (T3)

Electroencephalogram

Intervention Type DIAGNOSTIC_TEST

EEG monitoring throughout the entire simulation. The EEG recordings will be sampled at: Baseline (T0) During the simulation (T1) End of the debriefing (T2)

Interventions

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Electrocardiogram

two leads ECG

Intervention Type DIAGNOSTIC_TEST

Pupillometry

During the simulation, automatic pupillometry will be performed on all team members at the following time points: Baseline (T0) During the simulation (T1) End of the simulation (T2) End of the debriefing (T3)

Intervention Type DIAGNOSTIC_TEST

Electroencephalogram

EEG monitoring throughout the entire simulation. The EEG recordings will be sampled at: Baseline (T0) During the simulation (T1) End of the debriefing (T2)

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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ECG, EKG EEG

Eligibility Criteria

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Inclusion Criteria

* Medical trainees from the specialties of Emergency Medicine, Anesthesia and Intensive Care, Clinical Toxicology, Pediatrics, and Neonatology.
* Normal hearing and vision, or corrected to normal.

Exclusion Criteria

* Known history of psychiatric disorders, cognitive impairment, or cardiac arrhythmias.
* Current treatment with psychoactive, cardio-stimulant, or cardio-inhibitory medications.
* Significant stressful life events in the past six months (e.g., family bereavement).
* Previous systematic experience in meditation.
Minimum Eligible Age

25 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Antonio Gullì

Role: PRINCIPAL_INVESTIGATOR

Fondazione Policlinico Universitario A. Gemelli, IRCCS

Central Contacts

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Antonio Gulli', MD

Role: CONTACT

3288647390 ext. +39

Mariagiovanna Caporale, MD

Role: CONTACT

3889844590 ext. +39

References

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Champeroux P, Fesler P, Jude S, Richard S, Le Guennec JY, Thireau J. High-frequency autonomic modulation: a new model for analysis of autonomic cardiac control. Br J Pharmacol. 2018 Aug;175(15):3131-3143. doi: 10.1111/bph.14354. Epub 2018 Jun 15.

Reference Type BACKGROUND
PMID: 29723392 (View on PubMed)

Niskanen JP, Tarvainen MP, Ranta-Aho PO, Karjalainen PA. Software for advanced HRV analysis. Comput Methods Programs Biomed. 2004 Oct;76(1):73-81. doi: 10.1016/j.cmpb.2004.03.004.

Reference Type BACKGROUND
PMID: 15313543 (View on PubMed)

Other Identifiers

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ID7328

Identifier Type: -

Identifier Source: org_study_id

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