The T2D Profile - Studies of the Omics Profile in Type 2 Diabetes

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

52 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-06-15

Study Completion Date

2018-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The T2D Profile study examines the longitudinal molecular profiles of newly diagnosed type 2 diabetes (T2D), before and during guideline-based diabetes treatment.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Gene Expression Profiling and Bioinformatic Analysis Identifying Genes and Biochemical Pathways in Type 2 Diabetes

NCT00143013

Type 2 Diabetes

UNKNOWN

Development of Minimally Invasive Methodology for Diabetyping to Personalise Treatment to Realise Remission and Reversal of Type 2 Diabetes

NCT06125119

Type 2 Diabetes

RECRUITING

Determining Circadian Metabolic and Behavioural Rhythms in Patients with and Without Type 2 Diabetes

NCT06243172

Type 2 Diabetes Circadian Rhythm

RECRUITING

DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings

NCT02322762

Type 2 Diabetes Mellitus

COMPLETED

DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Setting in Japan

NCT02226822

Type 2 Diabetes Mellitus

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study included a total of 3 visits: At baseline and after 1 and 3 months of diabetes treatment according to standard of care. Visits included clinical examinations, questionnaires and clinical chemistry. In addition, samples were collected at each visits for comprehensive molecular profiling including proteomics, genomics, transcriptomics, metabolomics, lipidomics, antibody profiling, mass cytometry and gene profiling of fecal microbiota.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diabetes Mellitus, Type 2

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Signed informed consent to participate in the study.
* Age 50-65 years.
* T2D diagnosis (fasting p-glucose ≥7.0 mmol/L or an oral glucose tolerance test 2 hour p-glucose ≥11.1 mmol/L \[or ≥12.2 mmol/L if measured capillary\] at two separate occasions).

Exclusion Criteria

* Diabetes medication before study start.
* Severe hyperglycemia requiring hospitalization or immediate insulin treatment, as judged by the investigator.
* Presence of any clinically significant disease which, in the opinion of the investigator, may interfere with the subject´s ability to participate in the study.
* Any major surgical procedure or trauma within 4 weeks of the first study visit.

Minimum Eligible Age

50 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No