Intracardiac Echocardiography-Guided Catheter Ablation for Premature Ventricular Contractions Originating From the Papillary Muscles
NCT ID: NCT06898281
Last Updated: 2025-04-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
156 participants
INTERVENTIONAL
2025-03-23
2026-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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intracardiac echocardiography (ICE)-guided catheter ablation
Intracardiac echocardiography (ICE)-guided catheter ablation.
intracardiac echocardiography (ICE)-guided catheter ablation
Intracardiac echocardiography (ICE)-guided catheter ablation.
Pressure-sensing catheter ablation alone
Pressure-sensing catheter ablation alone.
Pressure-sensing catheter ablation alone
Pressure-sensing catheter ablation alone
Interventions
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intracardiac echocardiography (ICE)-guided catheter ablation
Intracardiac echocardiography (ICE)-guided catheter ablation.
Pressure-sensing catheter ablation alone
Pressure-sensing catheter ablation alone
Eligibility Criteria
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Inclusion Criteria
* Diagnosed with premature ventricular contractions (PVCs) originating from the papillary muscles.
* Symptoms refractory to antiarrhythmic drug therapy.
* Patients must be capable and willing to provide written informed consent for study participation.
Exclusion Criteria
* Ischemic heart disease, dilated cardiomyopathy, or hypertrophic cardiomyopathy.
* Severe hepatic or renal dysfunction:
AST/ALT \>3× upper limit of normal (ULN); Serum creatinine (SCr) \>3.5 mg/dl or creatinine clearance (Ccr) \<30 ml/min.
* Prior ablation for papillary muscle PVCs.
* Life expectancy \<1 year.
* Pregnancy or lactation.
18 Years
ALL
No
Sponsors
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The Second People's Hospital of Anhui Province
OTHER
The First People's Hospital of Hefei
OTHER
Qilu Hospital of Shandong University
OTHER
Fujian Medical University Union Hospital
OTHER
Chinese Academy of Medical Sciences, Fuwai Hospital
OTHER
Shanghai Chest Hospital
OTHER
Responsible Party
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Xu Liu
Professor
Locations
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Shanghai Chest Hospital
Shanghai, Xuhui, China
Countries
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Other Identifiers
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ICE-PMPVC
Identifier Type: -
Identifier Source: org_study_id
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