The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network

NCT ID: NCT06896019

Last Updated: 2025-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

37 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-01

Study Completion Date

2025-12-12

Brief Summary

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1. The difference of lung flora between the healthy group and the CAP group was compared, and the core flora involved in the development of CAP was identified.
2. To predict the metabolites associated with CAP.
3. Identification of genes related to immune response in CAP.
4. Construct the pulmonary microbiota - host interaction network with metabolites as the link.

Detailed Description

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Conditions

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Community Pneumonia

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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CAP

Community Pneumonia

Intervention Type DIAGNOSTIC_TEST

The BALF of CAP patients

Interventions

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Community Pneumonia

The BALF of CAP patients

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* According to the CAP clinical diagnostic criteria in the Guidelines for the Diagnosis and Treatment of Community-Acquired Pneumonia in Adults in China (2016 edition), cases eligible for community-acquired pneumonia were included and screened.

Exclusion Criteria

* Alveolar lavage fluid samples without electronic bronchoscopy were excluded for mNGS etiological examination of the case.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Sun Yat-sent Memorial Hospital

Guangzhou, Guangdong, China

Site Status

Countries

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China

Other Identifiers

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SYSKY-2024-628-01

Identifier Type: -

Identifier Source: org_study_id

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