Clinical Characteristics and Microbiology of Healthcare Associated Pneumonia

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

530 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-02-28

Study Completion Date

2013-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Background The prediction of multi-drug resistant (MDR) pathogens is a key issue in the management of health-care associated pneumonia (HCAP). Multiple risk factors have been proposed, some of which overlap with items of the pneumonia severity index (PSI). The aim of this study was to investigate the relationship between PSI and presence of MDR pathogens.

Methods Patients who were admitted to a tertiary-care hospital from January 2005 to December 2010 were screened by a discharge diagnosis of pneumonia. Patients were enrolled if they fulfilled the definition of HCAP by 2005 ATS/IDSA guideline.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Microbiology and Clinical Outcome of Pneumonia

NCT00873522

Pneumonia

UNKNOWN

The Predictive Value of Molecular Diagnostic Techniques in the Antimicrobial- Resistance Phenotypes of Pathogens

NCT07035535

Antimicrobial Drug Resistance High-Throughput Nucleotide Sequencing

ENROLLING_BY_INVITATION

Clinical Characteristics and Outcome of Patients With Community Acquired Pneumonia

NCT06716099

Community Acquired Pneumonia (CAP)

NOT_YET_RECRUITING

Metagenomic NGS for Diagnosis of Pneumonia

NCT05979350

Pneumonia Diagnosis

ACTIVE_NOT_RECRUITING NA

The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network

NCT06896019

Community Pneumonia

ACTIVE_NOT_RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

MDR bacteria were defined as Pseudomonas aeruginosa (P. aeruginosa), Enterobacter species, those not sensitive to second and third generation cephalosporins, Acinetobacter species, extended-spectrum β-lactamase (ESBL) Enterobacteriaceae such as Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae), Burkholderia cepacia (B. cepacia), Stenotrophomonas maltophilia (S. maltophilia), and methicillin resistant Staphylococcus aureus (MRSA).

The criteria for HCAP is defined as follows: patients who had been hospitalized in an acute care hospital for two or more days within the past 90 days; residents of a nursing home or long-term care facility; recipients of recent intravenous antibiotic therapy, chemotherapy or wound care within the past 30 days; or patients who attended a hospital or hemodialysis clinic.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthcare Associated Pneumonia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PSI II

PSI less than 70 or equal to 70

No interventions assigned to this group

PSI III

PSI 70-90

No interventions assigned to this group

PSI IV

PSI 90-130

No interventions assigned to this group

PSI V

PSI more than 130

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients who had been hospitalized in an acute care hospital for two or more days within the past 90 days;
* residents of a nursing home or long-term care facility;
* recipients of recent intravenous antibiotic therapy, chemotherapy or wound care within the past 30 days;
* or patients who attended a hospital or hemodialysis clinic.