Rapid Diagnosis of Severe Respiratory Tract Infectious Diseases and Screening of Biomarkers for Stratified Diagnosis

NCT ID: NCT06533514

Last Updated: 2024-08-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-01

Study Completion Date

2025-12-01

Brief Summary

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The purpose of this study is to clarify the biomarkers for rapid diagnosis and stratified diagnosis of severe respiratory tract infectious diseases through clinical experiments.

Detailed Description

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Methods: The relationship between relevant biomarkers and stratified diagnosis was analyzed by collecting laboratory and etiological examinations of patients with severe pneumonia.

Conditions

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Severe Pneumonia Biomarkers

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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mild

According to the APACHE II score, SOFA score and PSI score, the enrolled patients were divided into three groups: mild, moderate and severe.

No interventions assigned to this group

moderate

According to the APACHE II score, SOFA score and PSI score, the enrolled patients were divided into three groups: mild, moderate and severe.

No interventions assigned to this group

severe

According to the APACHE II score, SOFA score and PSI score, the enrolled patients were divided into three groups: mild, moderate and severe.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Meets the diagnostic criteria for severe pneumonia;
* Age≥18 years old and \< 80 years old;
* Willing to sign informed consent for the course of the study;

Exclusion Criteria

* Patients with intracranial hypertension, acute coronary syndrome, pleural fistula, pneumothorax, or subcutaneous emphysema;
* Pregnant and lactating patients;
* Severely hemodynamically unstable (an increase in vasopressors by more than 30% in the first 6 hours, or norepinephrine \>0.5mg/kg/min);
* Those who do not consent to participate in this study;
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese PLA General Hospital

OTHER

Sponsor Role lead

Responsible Party

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wang kaifei

Deputy chief physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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fei xie, doctor

Role: CONTACT

13911385976

Other Identifiers

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Pneumonia and Biomarkers

Identifier Type: -

Identifier Source: org_study_id

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