Causes and Outcomes of Community Acquired Pneumonia

NCT ID: NCT01336036

Last Updated: 2016-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-02-28

Study Completion Date

2014-02-28

Brief Summary

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This is a descriptive clinical research aiming:

* To describe the clinical spectrum and clinical characteristics of community acquired pneumonia (CAP) in patients admitted to hospital
* To identify the etiology of CAP and the antibiotic sensitivity of the isolated organisms
* To identify the risk factors that influence the severity of CAP

Detailed Description

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In Vietnam, the range and relative contribution of organisms causing CAP remain unclear, largely because diagnostic tools are limited and clinical research uncommon. An improved understanding of the risk factors, etiology and clinical outcomes of CAP in Vietnam would contribute to improved approaches to patient diagnosis and clinical management. This will be achieved by following the clinical and laboratory progress and treatment outcomes of in-patients diagnosed with CAP from admission to discharge. Comparative analyses will be between subgroups including survivor and non-survivor, severe CAP and non-severe CAP, known etiology and unknown etiology, SIRS, sepsis, severe sepsis and shock septic.

Conditions

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Community Acquired Pneumonia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients \> or = 18 years of age
* Patient meets the criteria of pneumonia (below), established within 36h of hospitalization
* Patient is not hospitalized or residing in a long-term-care facility within 14 days before the onset of symptoms
* Patient has not been at a referral hospital for \>2 days before admission to the study hospital
* Informed consent to participate in the study is provided

Exclusion Criteria

* Severe immunosuppression as judged by the enrolling physician (e.g. HIV, leukemia, lymphoma, chemotherapy for solid tumors, long-term corticosteroid use or other immunosuppressive drugs)
* Known active tuberculosis or current treatment for tuberculosis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oxford University Clinical Research Unit, Vietnam

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kinh V Nguyen, PhD

Role: PRINCIPAL_INVESTIGATOR

National Hospital of Tropical Diseases

Peter Horby, Dr.

Role: PRINCIPAL_INVESTIGATOR

Oxford University Clinical Research Unit - Hanoi

Rogier van Doorn, MD

Role: PRINCIPAL_INVESTIGATOR

Oxford University Clinical Research Unit

Locations

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National Hospital of Tropical Diseases

Hanoi, Hanoi, Vietnam

Site Status

Nguyen Tri Phuong Hospital

Ho Chi Minh City, , Vietnam

Site Status

Countries

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Vietnam

Related Links

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Other Identifiers

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03HN

Identifier Type: -

Identifier Source: org_study_id

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