The Effect of Aerobic Exercise on Bone Turnover Markers in Postmenopausal Patients
NCT ID: NCT06866561
Last Updated: 2025-03-12
Study Results
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Basic Information
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COMPLETED
NA
45 participants
INTERVENTIONAL
2022-11-15
2023-11-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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exercise group
The exercise group participated in a supervised aerobic exercise program consisting of walking on a treadmill for 30 minutes per day, 3 days per week, at an intensity of 40-60% of maximal heart rate for 4 weeks.
aerobic exercise
The exercise group participated in a supervised aerobic exercise program consisting of walking on a treadmill for 30 minutes per day, 3 days per week, at an intensity of 40-60% of maximal heart rate for 4 weeks. Additionally, they were shown an exercise program at the initial assessment that included balance, posture, and endurance exercises using body weight and weights to be performed 3 days a week, with 3 sets of 10 repetitions. The control group did not participate in any exercise program.
cholecalciferol
Participants were prescribed 2000 IU of vitamin D (cholecalciferol) daily for 12 weeks.
calcium carbonate
Participants were prescribed 1200 mg of calcium carbonate daily for 12 weeks.
Control group
The control group did not participate in any exercise program.
cholecalciferol
Participants were prescribed 2000 IU of vitamin D (cholecalciferol) daily for 12 weeks.
calcium carbonate
Participants were prescribed 1200 mg of calcium carbonate daily for 12 weeks.
Interventions
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aerobic exercise
The exercise group participated in a supervised aerobic exercise program consisting of walking on a treadmill for 30 minutes per day, 3 days per week, at an intensity of 40-60% of maximal heart rate for 4 weeks. Additionally, they were shown an exercise program at the initial assessment that included balance, posture, and endurance exercises using body weight and weights to be performed 3 days a week, with 3 sets of 10 repetitions. The control group did not participate in any exercise program.
cholecalciferol
Participants were prescribed 2000 IU of vitamin D (cholecalciferol) daily for 12 weeks.
calcium carbonate
Participants were prescribed 1200 mg of calcium carbonate daily for 12 weeks.
Eligibility Criteria
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Inclusion Criteria
* Bone mineral density (BMD) T-scores between -1 and -2.5 ( measured by dual-energy X-ray absorptiometry)
Exclusion Criteria
* A history of traumatic or nontraumatic fractures in the past year,
* Thyroid hormone disorders,
* Parathyroid hormone disorders,
* Liver function disorders,
* Kidney function disorders,
* Chronic heart failure,
* A history of malignancy,
* A history of rheumatological diseases,
* Corticosteroid use,
* Immunosuppressive drug use,
* Anticonvulsant and heparin use,
* Antiresorptive or anabolic agent treatments use
* Hormone replacement therapy use
* Those who could not complete sessions due to mechanical pain exacerbated during aerobic exercise on a treadmill (such as knee and hip osteoarthritis, back pain, etc)
45 Years
65 Years
FEMALE
Yes
Sponsors
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Bursa Yuksek Ihtisas Training and Research Hospital
OTHER_GOV
Responsible Party
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KÜBRA NUR DENİZ
Principal Investigator
Principal Investigators
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Kübra Nur Deniz, M.D.
Role: PRINCIPAL_INVESTIGATOR
Bursa Yuksek Ihtisas Training and Research Hospital
Locations
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Bursa Yüksek İhtisas Education and Research Hospital
Bursa, Yıldırım, Turkey (Türkiye)
Countries
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References
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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HSBY-FTR-KND-01
Identifier Type: -
Identifier Source: org_study_id
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