Effect of Aerobic Exercise Versus Resistance Exercise on Bone Density in Postmenopausal Diabetic Women

NCT ID: NCT06505044

Last Updated: 2025-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-10

Study Completion Date

2024-08-01

Brief Summary

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Osteoporosis is a significant public health issue, especially among postmenopausal women with diabetes, and its prevalence is increasing. This trial aims to determine the influence of moderate intensity aerobic exercise vs resistance exercise on bone mineral density among postmenopausal diabetic women.

Detailed Description

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has diabetes. Postmenopausal Osteoporosis (PMO) is an increasingly serious metabolic bone disease in the world, which generally develops in middle-aged and elderly women and postmenopausal women, and it is characterized by low bone mass and microstructure degradation of bone tissues. there are complex pathophysiological effects between them: T2D directly affects bone metabolism and strength. Some antidiabetic drugs affect bone metabolism, and diabetes complications are related to the risk of falls and subsequent fractures. Patients with T2D have higher trabecular and lower cortical bone density, leading to lower bone intensity. Exercise is considered a highly relevant component in the prevention and treatment of osteoporosis and fracture reduction. Exercise greatly affects bone geometry as it increases periosteal apposition through increasing osteoblast formation. In addition to influencing bone mineral density, exercise can improve muscle function to potentially decrease fall risk through improved balance and strength.

The purpose of this study was to investigate the effect of moderate-intensity aerobic exercise versus resistance exercise on bone mineral density in postmenopausal diabetic women.

Conditions

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Osteoporosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
Double-blind masking the patient was not be informed about the training group or the other group; they will be evaluated and trained at different places and times.

Study Groups

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Group (A)

25 patients receive aerobic exercise attended the program of walking on a treadmill machine for eight weeks according to specific parameters, in addition to their usual daily calcium intake.

Group Type EXPERIMENTAL

aerobic exercise

Intervention Type PROCEDURE

aerobic exercise.

* Intensity: according to heart rate (60-75% of maximum heart rate) MHR=220-age.
* Heart rate: determined by the sensor of a treadmill.
* Duration: 40-50 min per session. Each session consisted of 5-10 minutes of warming up exercise on a treadmill without increasing speed or intensity and the same for the cooling down phase. There was 30 minutes of conditioning exercise including increasing the treadmill speed till reaching (60-75%) of the maximum heart rate.
* Frequency: 3 times/week for 12 weeks in addition to their usual daily calcium intake.

resistance exercise

Intervention Type PROCEDURE

resisted exercise program for 12 weeks

Group (B)

25 patients receive resisted exercise in addition to their usual daily calcium intake for 12 weeks.

Group Type ACTIVE_COMPARATOR

aerobic exercise

Intervention Type PROCEDURE

aerobic exercise.

* Intensity: according to heart rate (60-75% of maximum heart rate) MHR=220-age.
* Heart rate: determined by the sensor of a treadmill.
* Duration: 40-50 min per session. Each session consisted of 5-10 minutes of warming up exercise on a treadmill without increasing speed or intensity and the same for the cooling down phase. There was 30 minutes of conditioning exercise including increasing the treadmill speed till reaching (60-75%) of the maximum heart rate.
* Frequency: 3 times/week for 12 weeks in addition to their usual daily calcium intake.

resistance exercise

Intervention Type PROCEDURE

resisted exercise program for 12 weeks

Interventions

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aerobic exercise

aerobic exercise.

* Intensity: according to heart rate (60-75% of maximum heart rate) MHR=220-age.
* Heart rate: determined by the sensor of a treadmill.
* Duration: 40-50 min per session. Each session consisted of 5-10 minutes of warming up exercise on a treadmill without increasing speed or intensity and the same for the cooling down phase. There was 30 minutes of conditioning exercise including increasing the treadmill speed till reaching (60-75%) of the maximum heart rate.
* Frequency: 3 times/week for 12 weeks in addition to their usual daily calcium intake.

Intervention Type PROCEDURE

resistance exercise

resisted exercise program for 12 weeks

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Fifty women postmenopausal obese women
* (BMI) 30 -35 kg/m2
* their age ranges from 50 to 60 years old and
* complain of diabetic type 2 for 10 years ago.

Exclusion Criteria

* women with renal or liver disease,
* cardiac or chest disease psychological problems,
* cognitive problems are excluded from the study.
* Any women who have therapeutic problems that will interfere with performing exercise or affection BMD will be excluded from this study.
Minimum Eligible Age

50 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Deraya University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Soad A. Mohamad

Minya, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Physical Therapy

Identifier Type: -

Identifier Source: org_study_id

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