Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis
NCT ID: NCT06864390
Last Updated: 2025-03-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
114 participants
INTERVENTIONAL
2025-04-30
2025-11-30
Brief Summary
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The participants will be evaluated by numeric rating scale and oxford knee score for assessment of pain relief up to 16 weeks.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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genicular nerve phenol neurolysis
chemical neurolysis using 2 mL of 9% phenol solution prepared from crystallized phenol will be applied to each genicular nerve.
genicular nerve neurolysis
The superior medial genicular nerve (SMGN), superior lateral genicular nerve (SLGN), and inferior medial genicular nerve (IMGN) will be blocked either by phenol neurolysis or radiofrequency ablation
genicular nerve radiofrequency ablation
Radiofrequency thermocoagulation will be applied to each nerve at 80 degrees for 90 seconds.
genicular nerve neurolysis
The superior medial genicular nerve (SMGN), superior lateral genicular nerve (SLGN), and inferior medial genicular nerve (IMGN) will be blocked either by phenol neurolysis or radiofrequency ablation
Interventions
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genicular nerve neurolysis
The superior medial genicular nerve (SMGN), superior lateral genicular nerve (SLGN), and inferior medial genicular nerve (IMGN) will be blocked either by phenol neurolysis or radiofrequency ablation
Eligibility Criteria
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Inclusion Criteria
* Failure to manage pain with conservative methods.
Exclusion Criteria
* Patients with cardiac pacemakers or implantable cardiac defibrillators.
* Septic knee or systemic sepsis.
* Allergy to any of the drugs used in the study.
* Coagulopathy or patients on anticoagulants.
* Patients with psychiatric illness.
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Principal Investigators
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Ahmed Boeith, MD
Role: PRINCIPAL_INVESTIGATOR
Ain Shams University
Central Contacts
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Other Identifiers
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FMASU R17/2025
Identifier Type: -
Identifier Source: org_study_id
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