Interdialytic Resistance Exercises in with Chronic Kidney Diseases

NCT ID: NCT06862336

Last Updated: 2025-03-06

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-01-20
• Study Completion Date: 2025-04-01

Brief Summary

Fifty chronic kidney disease patients' ages will range from 40 to 55 years. They will be selected from the dialysis unit. received intra-dialytic combined exercise program for 8 weeks(3 sessions/week), with their medical treatment.

Conditions

Chronic Kidney Diseases

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Group A

twenty-five patients with CKD will receive intra-dialytic combined exercise program for8 weeks(3 sessions/week), with their medical treatment.

Group Type: EXPERIMENTAL

intra-dialytic exercise program associated with medical treatment

Intervention Type: PROCEDURE

• Stretch for pectorals and calf muscles: Two sets - 3 times/ set.
• Breathing exercises associated with upper limb movement.
• Resistive exercise for hip abductors, hip flexors, and calf muscles by using theraband.
• Sit to stand strengthening exercises: -

Group B

twenty-five patients with CKD will receive the inter-dialytic combined exercise program with their medications.

Group Type: PLACEBO_COMPARATOR

inter-dialytic combined exercise program with their medications

Intervention Type: PROCEDURE

receive the inter-dialytic combined exercise program with their medications. Like the study group except for diaphragmatic breathing instead of breathing with upper limb exercise.

Interventions

intra-dialytic exercise program associated with medical treatment

• Stretch for pectorals and calf muscles: Two sets - 3 times/ set.
• Breathing exercises associated with upper limb movement.
• Resistive exercise for hip abductors, hip flexors, and calf muscles by using theraband.
• Sit to stand strengthening exercises: -

Intervention Type: PROCEDURE

inter-dialytic combined exercise program with their medications

receive the inter-dialytic combined exercise program with their medications. Like the study group except for diaphragmatic breathing instead of breathing with upper limb exercise.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

1. Fifty patients with CKD, are on hemodialysis for longer than threemonths 3 sessions/ week.

2. Theirageswillrangefrom40 to 55yearsold.

3. Their body mass index is more than 18.5 and less than 29.9 %.

3-All patients have hemodynamic stability over the month before beginning the program.

Exclusion Criteria

• 1. Severe Chest diseases(either obstructive or restrictive). 2. Clinical signs of a severe cardiac event.(eg, severe atherosclerosis, congestive heart failure), 3. Severepsychiatricorcognitiveimpairment,whounabletofollowcomment. 4. Neurological disorders affecting respiratory muscles or any muscular dystrophies(cervical disc or bulge).

5. Patients with severe self-limiting illness (e.g., cancer). 6. peripheral artery disease in lower extremities. 7. Systolic blood pressure < 180 mmHg, diastolic blood pressure more than 105 mmHg, or heart rate above 120 bpm during dialysis.

8. Patient with uncontrolled- diabetes.

• Minimum Eligible Age: 40 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Amira saad mohamed

lecturer of physical therapy

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Cairo University

Giza, , Egypt

Countries

Egypt

Other Identifiers

012/005019

Identifier Type: -

Identifier Source: org_study_id