Effect of Intradialytic Exercises in Chronic Kidney Disease Patients

NCT ID: NCT06293092

Last Updated: 2024-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-30

Study Completion Date

2024-01-30

Brief Summary

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the purpose of this study is to compare between intradialytic aerobic versus resistive exercises on immunity response in patients with chronic kidney disease.

Detailed Description

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The patients of this study will randomly assigned into three equal groups (n=20)

1. Study Group A (20 patients) will receive intradialytic aerobic exercise and medical treatment.
2. Study Group B (20 patients) will receive intradialytic resistive exercise and medical treatment.
3. Control Group C (20 patients) will receive medical treatment only (HD session and drugs) Each patient will receive the treatment program three times per week for three months.

Conditions

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Chronic Kidney Disease stage3

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

control group receive medical treatment only ,first study group receive medical treatment and intradialytic aerobic exercise , second study group receive medical treatment and intradialytic resistive exercise
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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control group C

receive hemodialysis sessions

Group Type EXPERIMENTAL

hemodialysis sessions

Intervention Type DEVICE

hemodialysis sessions ,each patient will receive the treatment program three times per week for three months.

study group A aerobic exercise

receive hemodialysis sessions and intradialytic aerobic exercise

Group Type EXPERIMENTAL

leg pedaling cycling device

Intervention Type DEVICE

Intradialytic aerobic cycling exercise program ,each patient will receive the treatment program three times per week for three months.

hemodialysis sessions

Intervention Type DEVICE

hemodialysis sessions ,each patient will receive the treatment program three times per week for three months.

study group B resistive exercise

receive hemodialysis sessions and intradialytic resistive exercise

Group Type EXPERIMENTAL

sand bags

Intervention Type DEVICE

Intradialytic resistive exercise program , each patient will receive the treatment program three times per week for three months.

hemodialysis sessions

Intervention Type DEVICE

hemodialysis sessions ,each patient will receive the treatment program three times per week for three months.

Interventions

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leg pedaling cycling device

Intradialytic aerobic cycling exercise program ,each patient will receive the treatment program three times per week for three months.

Intervention Type DEVICE

sand bags

Intradialytic resistive exercise program , each patient will receive the treatment program three times per week for three months.

Intervention Type DEVICE

hemodialysis sessions

hemodialysis sessions ,each patient will receive the treatment program three times per week for three months.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Sixty men chronic kidney disease (grade III RF). They received regular hemodialysis sessions at least one year ago, each one for four hours, three times per week.
* They had a history of type II Diabetes more than five years.
* Their age will be ranged from 50-60 years old.
* They are Fit for exercise by functional assessment using six minute walk test.
* Their Hemoglobin level more than 10 g\\dl.
* Their Body Mass Index (BMI) will be ranged from "18.5" to "24.9".

Exclusion Criteria

* Severe cardiac disorders.
* Severe orthopedic problems (for example fractures).
* Hepatic encephalopathy.
* Preexisting neuromuscular diseases (e.g. myasthenia gravis). •Severe chest diseases.
* Spinal cord injuries involved the phrenic nerve.
* Uncontrolled diabetes or hypertension
* Patients receiving inefficient hemodialysis session.
* Patients with other cause for inflammation e.g. malignancy and autoimmune disease.
* Active bleeding as alveolar hemorrhage, hemoptysis.
* Physical limitation that would limit cycling.
Minimum Eligible Age

50 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Hazem Mohamed Yasin Abbas

physiotherapist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Fayoum hospital

Al Fayyum, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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P.T.REC/012/004008

Identifier Type: -

Identifier Source: org_study_id

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