The Impact of Chronic E-Cigarette Usage on Microvascular Health

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

44 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-07-14

Study Completion Date

2026-02-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study is focused on investigating the mechanisms involved in microvascular health in subjects that use e-cigarettes frequently. To explore microvascular health, different techniques and compounds. For one of the tests, iontophoresis, the drug's use will be stored and handled as described by the approved IND and non-IDS plan.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Investigation of the Effects of Electronic Cigarettes on Vascular Health

NCT03041493

Vascular Health

TERMINATED NA

Sex Differences in the Vascular Effects of E-cigarette Use

NCT06159608

E-cigarette Use

RECRUITING EARLY_PHASE1

Acute Effects of E-Cigarette Aerosol Inhalation

NCT03479203

Endothelial Dysfunction Biochemical Markers

COMPLETED EARLY_PHASE1

Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers

NCT03625986

Tobacco Dependence

COMPLETED NA

Vascular Effects of a Single Bout of Electronic Cigarette Use

NCT03209661

Arterial Stiffness

COMPLETED PHASE1

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Electronic cigarettes or e-cigarettes have become increasingly popular, due to their promotion as a healthy alternative to traditional tobacco cigarettes. However, there are large discrepancies of knowledge in understanding how these e-cigarettes affect the subjects health and the way their body uses oxygen. The overall goal of this study is to evaluate e-cigarettes usage on subjects health.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

E-Cig Use

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Chronic e-cigs users

Used e-cigarettes with nicotine (≥3 times/week for ≥6 months)

E-cig use

Intervention Type OTHER

Based on e-cigarette usage, participants will be divided into those who used e-cigarettes and those who did not use e-cigarettes

Never Users

Use of cigarettes or other tobacco products less than 50 times in their lifetime.

E-cig use

Intervention Type OTHER

Based on e-cigarette usage, participants will be divided into those who used e-cigarettes and those who did not use e-cigarettes

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

E-cig use

Based on e-cigarette usage, participants will be divided into those who used e-cigarettes and those who did not use e-cigarettes

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Between 18 and 29 years of age
* Used e-cigarettes with nicotine (≥3 times/week for ≥6 months)

Exclusion Criteria

* 17 years old and younger or 30 years old or older.
* Former combustible tobacco user/ former smoker
* Use of cigarettes for 15 days or more in the past 60 days
* Use of other tobacco products (cigars, hookah, smokeless), marijuana and/or illicit or prescription drugs weekly or more frequently in the past 60 days
* Evidence of cardiovascular, pulmonary, renal, hepatic, metabolic, cerebral diseases or sleep disorders
* Disorder or use of medication that affects cardiopulmonary health
* Evidence of pregnancy or current nursing

Non e-Cig using arm

Inclusion

\- Between 18 and 29 years of age

Exclusion

* 17 years old and younger or 30 years old and older
* Use of cigarettes or other tobacco products more than 50 times in their lifetime.
* Evidence of cardiovascular, pulmonary, renal, hepatic, metabolic, cerebral diseases or sleep disorders
* Disorder or use of medication that affects cardiopulmonary health
* Evidence of pregnancy or current nursing

Minimum Eligible Age

18 Years

Maximum Eligible Age

29 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes