Effects of Electronic Cigarette Settings and Liquid Concentrations in Cigarette Smokers and Electronic Cigarette Users
NCT ID: NCT03710590
Last Updated: 2022-10-06
Study Results
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View full resultsBasic Information
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COMPLETED
NA
45 participants
INTERVENTIONAL
2019-01-15
2020-03-09
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
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Cigarette smokers
ECIG Lab Session 15 watts, 10 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 15 watts, 15 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.).
ECIG Lab Session 15 watts, 30 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 10 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 15 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 30 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
Electronic cigarette users
ECIG Lab Session 15 watts, 10 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 15 watts, 15 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.).
ECIG Lab Session 15 watts, 30 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 10 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 15 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 30 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
Interventions
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ECIG Lab Session 15 watts, 10 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 15 watts, 15 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.).
ECIG Lab Session 15 watts, 30 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 10 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 15 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
ECIG Lab Session 30 watts, 30 mg nicotine
During each session, participants will first complete a 10-puff product use bout, and then a 90-minute ad lib product use bout.
Eligibility Criteria
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Inclusion Criteria
* between the ages of 18-55
* willing to provide informed consent
* able to attend the lab and abstain from tobacco/nicotine as required and must agree to use designated products according to study protocol
Exclusion Criteria
* Individuals who weigh less than 110 pounds
Some study details about the eligibility criteria are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.
18 Years
55 Years
ALL
Yes
Sponsors
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National Institute on Drug Abuse (NIDA)
NIH
Virginia Commonwealth University
OTHER
Responsible Party
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Principal Investigators
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Alison Breland, PhD
Role: PRINCIPAL_INVESTIGATOR
Virginia Commonwealth University
Locations
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Clinical Behavioral Pharmacolgy Laboratory
Richmond, Virginia, United States
Countries
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References
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Eversole A, Budd S, Karaoghlanian N, Lipato T, Eissenberg T, Breland AB. Interactive effects of protonated nicotine concentration and device power on ENDS nicotine delivery, puff topography, and subjective effects. Exp Clin Psychopharmacol. 2023 Apr;31(2):443-454. doi: 10.1037/pha0000576. Epub 2022 Jun 13.
Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Document Type: Informed Consent Form
Other Identifiers
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HM20012738
Identifier Type: -
Identifier Source: org_study_id
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