Adolescent Vaping Characterization and Parent Views on Adolescent Vaping Protocol

NCT ID: NCT05669716

Last Updated: 2025-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Total Enrollment

726 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-09

Study Completion Date

2025-09-25

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Background:

The use of electronic cigarettes (vaping) has increased among adolescents over the past decade. Vaping raises many health concerns. People who vape inhale toxic chemicals. Vaping is also linked with mental health issues, such as depression and suicide risk. In one survey, 85% of young adults reported that they used both vaping and tobacco products; the primary reason they cited for using these products was stress.

Objective:

This natural history study will survey adolescents and their parents about their attitudes toward vaping.

Eligibility:

People aged 13 to 18, including those who vape; those who once vaped; and those who have never vaped. Parents of people aged 13 to 18 who are known or suspected of vaping are also needed.

Design:

Participants will take a survey. They will use their own smartphone, computer, or tablet to answer questions. The survey will take about 20 minutes. Their answers will be anonymous.

Teenage participants will answer questions on different topics:

Vaping habits, such as when and how they vape.

Drug use, including nicotine, cannabis, and alcohol.

Mood issues, such as depression, anxiety, and stress.

Social influences on vaping, including perceived attitudes of parents and peers.

Other leisure habits, including online gaming and use of social media.

Parents will answer similar questions.

A phone number and links will be given to participants who need help for suicidal thoughts. Other links will be given to those who want help with parenting resources or aids to quit vaping.

Participants may be invited to take part in an 8-week course on mindfulness-based stress reduction.

Participants who finish the survey will receive 10 dollars.

...

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Study Description: This protocol will explore characteristics of adolescents who vape and the attitudes of adolescents and parents of adolescents who vape towards adolescent vaping, focusing on the Baltimore area. Hypotheses: (Adolescent) Currently vaping adolescents will not view vaping as a problem for which they seek help and will have more mental health symptoms than non-vaping adolescents, while non-vaping adolescents will view vaping more negatively with formerly vaping adolescents scoring between the currently vaping and non-vaping adolescent groups. (Parent) Parents who vape will be more likely to approve of their adolescent s vaping than non-vaping parents.

Objectives:

Primary Objective: To characterize adolescent vaping patterns, overall drug use, perceived stress, and awareness of mindfulness meditation.

Secondary Objectives: To characterize the mental health symptoms of currently vaping, formerly vaping and non-vaping adolescents, and to characterize parent attitudes towards their adolescent s vaping.

Endpoints:

Primary Endpoint: An adequate description of adolescent vapers habits and attitudes towards their vaping.

Secondary Endpoints: An adequate comparison of adolescent vapers, former vapers and non-vapers and of parental attitudes towards adolescent vapers.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthy Volunteers Vaping Teens

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Vape Nicotine Teen Drug Use Natural History

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

parents of teens who vape

400 parent participants, defined as an adult who identifies as parenting an adolescent aged 13-17 whom they know/suspect is vaping.

No interventions assigned to this group

teens who formerly vaped

Adolescents N=400 (formerly vaped)

No interventions assigned to this group

teens who never vaped

Adolescents N=400 (never vaped).

No interventions assigned to this group

teens who vape

adolescent participants (minor subjects), comprised of N=400 (currently vaping, defined as vaping at least one day in the previous 30-day period

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

In order to be eligible to participate in this study, an individual must:

Be an adolescent age 13-18 and in grades 8-12 or the summer after graduation, OR an adult who identifies as parenting an adolescent aged 13-18 and in grades 8-12 or the summer after graduation whom they know/suspect is vaping or never has vaped. All participants must be willing to complete the survey to the end.

Exclusion Criteria

Non-English speakers cannot participate in this study. Justification: The questionnaires from which the survey is constructed are not all validated in languages other than English. We do not have the resources to translate the consent and surveys.

Those who cannot demonstrate understanding of the purpose of the survey by answering questions after a brief explanation will be excluded. Justification: The ability to understand the purpose of the survey is required in order to provide informed consent to participate and to be able to provide meaningful answers to the survey questions.
Minimum Eligible Age

13 Years

Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Betty Jo Salmeron, M.D.

Role: PRINCIPAL_INVESTIGATOR

National Institute on Drug Abuse (NIDA)

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

National Institute on Drug Abuse

Baltimore, Maryland, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

001196-DA

Identifier Type: -

Identifier Source: secondary_id

10001196

Identifier Type: -

Identifier Source: org_study_id