Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation
NCT ID: NCT06855758
Last Updated: 2025-03-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
150 participants
INTERVENTIONAL
2025-03-06
2027-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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dopamine
Continuous using of dopamine as blood pressure regulation after anesthesia, with dosage adjusted according to intraoperative needs
No interventions assigned to this group
terlipressin + dopamine
Terlipressin was given before the graft circulation was established while continuous using of dopamine during the whole operation
terlipressin
Terlipressin was given prior to the opening of the graft circulation (with the possibility of reperfusion hypotension) when the blood pressure is suboptimal and does not respond well to dobutamine or fluid volume resuscitation. 1 mg terlipressin + 100 ml of sodium chloride injections was given for intravenous infusion.
Interventions
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terlipressin
Terlipressin was given prior to the opening of the graft circulation (with the possibility of reperfusion hypotension) when the blood pressure is suboptimal and does not respond well to dobutamine or fluid volume resuscitation. 1 mg terlipressin + 100 ml of sodium chloride injections was given for intravenous infusion.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* known allergy to study medication
* known pregnancy status
* cancellation of surgery due to grafts or personal reasons
* persistent severe preoperative hypertension that may not require intraoperative supportive therapy with vasoactive medications
* any other reason that the supervising physician or the anesthesiologist on duty think the patient is not suitable for the study
18 Years
ALL
No
Sponsors
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Beijing Friendship Hospital
OTHER
Responsible Party
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Principal Investigators
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Fushan Xue
Role: PRINCIPAL_INVESTIGATOR
Department of Anesthesiology, Beijing Friendship Hospital
Locations
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Beijing Friendship Hospital
Beijing, , China
Countries
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Central Contacts
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Other Identifiers
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2025-P2-023-01
Identifier Type: -
Identifier Source: org_study_id
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